Comparative evidence
Compare conditions
Put two canonical disease records side by side. The result is a shareable, deterministic comparison of what is shared, what is unique, and how much evidence each record currently carries.
- 21%
- weighted overlap
- 20
- shared signals
Comparison
Crohn's DiseaseandObesity
1 references occur in both reconciled evidence sets. Shared signals do not establish shared causes, diagnoses, or treatments.
- 25
- Crohn's Disease references
- 31
- Obesity references
- 1
- shared references
Metals depleted or redistributed
1 sharedTaxa enriched
3 sharedShared
Only in Crohn's Disease
Only in Obesity
Taxa depleted
4 sharedShared
Only in Crohn's Disease
Only in Obesity
Host response elevated
4 sharedShared
Only in Crohn's Disease
Only in Obesity
Host response depleted
1 sharedShared
Only in Crohn's Disease
Anti Inflammatory CytokinesAlpha Defensins
Only in Obesity
Ecological state
2 sharedShared
Only in Crohn's Disease
Barrier DysfunctionLeaky GutBiofilmSCFA DepletionBile Acid DysmetabolismTryptophan DepletionFerroptosisButyrate CollapseNOD2 Paneth Cell Defect
Only in Obesity
Metal Driven DysbiosisReduced SCFA ProductionIncreased LPSEndotoxemiaIntestinal Permeability IncreaseAcidic MicroenvironmentMetabolic EndotoxemiaReduced Microbial DiversityIncreased Energy HarvestBile Acid DysregulationVirome Depletion
Virulence and functional enzymes
2 sharedShared
Only in Crohn's Disease
Zinc-MetalloproteaseIron Dependent HydrogenaseCobalt Dependent EnzymesCopper Resistance DeterminantsMucin Degrading EnzymesSiderophores EnterobactinSiderophores YersiniabactinSiderophores AerobactinZinc Metalloprotease BFTFimH AdhesinOuter Membrane Vesicles