Comparative evidence

Compare conditions

Put two canonical disease records side by side. The result is a shareable, deterministic comparison of what is shared, what is unique, and how much evidence each record currently carries.

8%: weighted overlap
6: shared signals

First condition

Second condition

Comparison

Colorectal CancerandIrritable Bowel Syndrome (IBS)

0 references occur in both reconciled evidence sets. Shared signals do not establish shared causes, diagnoses, or treatments.

36: Colorectal Cancer references
7: Irritable Bowel Syndrome (IBS) references
0: shared references

Metals elevated or accumulated

1 shared

Shared

Nickel

Only in Colorectal Cancer

Iron Zinc Cadmium Lead Copper Arsenic Chromium

Only in Irritable Bowel Syndrome (IBS)

None indexed

Metals depleted or redistributed

1 shared

Shared

Zinc

Only in Colorectal Cancer

Butyrate Selenium Manganese

Only in Irritable Bowel Syndrome (IBS)

None indexed

Taxa enriched

1 shared

Taxa depleted

3 shared

Shared

Faecalibacterium prausnitzii Bifidobacterium Lactobacillus

Only in Colorectal Cancer

Lachnospiraceae Roseburia Prevotella copri Ruminococcus albus Dialister Ruminococcus

Only in Irritable Bowel Syndrome (IBS)

None indexed

Host response elevated

0 shared

Shared

None indexed

Only in Colorectal Cancer

IL 6TNF-alpha (Tumor Necrosis Factor Alpha)IL-1beta (Interleukin-1 Beta)Lipopolysaccharide Calprotectin (S100A8/A9)Hepcidin Lipocalin-2

Only in Irritable Bowel Syndrome (IBS)

Mast Cell MediatorsHistamineTryptaseSerotonin

Host response depleted

0 shared

Shared

None indexed

Only in Colorectal Cancer

IL-10 (Interleukin-10)IgATreg CellsSelenium Dependent Glutathione PeroxidaseGlutathione (GSH)

Only in Irritable Bowel Syndrome (IBS)

Zinc Dependent Defensins

Ecological state

0 shared

Shared

None indexed

Only in Colorectal Cancer

Hypoxia BiofilmSecondary Bile Acid AccumulationFermentative Acidic MicroenvironmentEpithelial Barrier DisruptionColonic Serotonin DepletionAnaerobic DominanceSecondary Bile Acid ExcessSCFA DepletionWarburg EffectCross Kingdom DysbiosisVirome Network Disruption

Only in Irritable Bowel Syndrome (IBS)

Nickel Allergic Contact MucositisMast Cell Nerve AxisSIBOVisceral HypersensitivityFermentative DysbiosisBarrier Dysfunction

Virulence and functional enzymes

0 shared

Shared

None indexed

Only in Colorectal Cancer

FadAFap2LPS TLR4BFT ToxinColibactin PksSiderophores Urease Glyoxalase I Beta-GlucuronidaseBFT Zinc MetalloproteaseColibactin GenotoxinFadA AdhesinFap2 LectinNAD(P)H Oxidase

Only in Irritable Bowel Syndrome (IBS)

TLR4 Nickel ActivationMast Cell Degranulation Mediators