Comparative evidence
Compare conditions
Put two canonical disease records side by side. The result is a shareable, deterministic comparison of what is shared, what is unique, and how much evidence each record currently carries.
- 23%
- weighted overlap
- 25
- shared signals
Comparison
Alzheimer's DiseaseandCrohn's Disease
0 references occur in both reconciled evidence sets. Shared signals do not establish shared causes, diagnoses, or treatments.
- 31
- Alzheimer's Disease references
- 25
- Crohn's Disease references
- 0
- shared references
Metals depleted or redistributed
3 sharedShared
Only in Alzheimer's Disease
Only in Crohn's Disease
Taxa enriched
3 sharedShared
Only in Alzheimer's Disease
Only in Crohn's Disease
Taxa depleted
3 sharedShared
Only in Alzheimer's Disease
Only in Crohn's Disease
Host response elevated
3 sharedShared
Only in Alzheimer's Disease
Proinflammatory CytokinesTransferrin Receptor AlteredFerritin AlteredTREM2
Only in Crohn's Disease
Host response depleted
1 sharedShared
Only in Alzheimer's Disease
Only in Crohn's Disease
Anti Inflammatory CytokinesAlpha Defensins
Ecological state
4 sharedShared
Only in Alzheimer's Disease
DysbiosisNeuroinflammationAmyloid SeedingMicroglial ActivationLPS TranslocationBlood Brain Barrier DisruptionAmyloid Cross SeedingLPS EndotoxemiaTMAO ElevationEpigenetic Latency
Only in Crohn's Disease
Leaky GutBiofilmBile Acid DysmetabolismTryptophan DepletionFermentative MetabolismButyrate CollapseNOD2 Paneth Cell Defect
Virulence and functional enzymes
2 sharedShared
Only in Alzheimer's Disease
Curli FibersLipopolysaccharideBacterial AmyloidsUreaseMetalloproteasesCurli AmyloidLPSBeta-Glucuronidase
Only in Crohn's Disease
Zinc-MetalloproteaseIron Dependent HydrogenaseCobalt Dependent EnzymesCopper Resistance DeterminantsMucin Degrading EnzymesSiderophores EnterobactinSiderophores YersiniabactinSiderophores AerobactinZinc Metalloprotease BFTFimH AdhesinOuter Membrane Vesicles