Comparative evidence
Compare conditions
Put two canonical disease records side by side. The result is a shareable, deterministic comparison of what is shared, what is unique, and how much evidence each record currently carries.
- 15%
- weighted overlap
- 12
- shared signals
Comparison
Ulcerative ColitisandDepression
2 references occur in both reconciled evidence sets. Shared signals do not establish shared causes, diagnoses, or treatments.
- 6
- Ulcerative Colitis references
- 38
- Depression references
- 2
- shared references
Metals depleted or redistributed
2 sharedTaxa enriched
1 sharedShared
Only in Ulcerative Colitis
Only in Depression
Taxa depleted
2 sharedShared
Only in Ulcerative Colitis
Only in Depression
Host response elevated
3 sharedHost response depleted
3 sharedShared
Only in Ulcerative Colitis
None indexed
Only in Depression
Ecological state
0 sharedShared
None indexed
Only in Ulcerative Colitis
Iron Pathobiont Feedback LoopButyrate DepletionMucosal UlcerationBarrier DysfunctionTh17 Treg ImbalanceMucin Degradation
Only in Depression
DysbiosisLeaky GutIntestinal PermeabilityEndotoxemiaLow SCFA ProductionImpaired Tryptophan MetabolismReduced Indole ProductionHPA Axis DysregulationTryptophan Shunting IDOSCFA DepletionHPA Axis HyperactivationBlood Brain Barrier DisruptionNeuroinflammation
Virulence and functional enzymes
0 sharedShared
None indexed
Only in Ulcerative Colitis
Only in Depression
TryptophanaseBeta-GlucuronidaseLPS BiosynthesisPro Inflammatory Metabolite SynthesisBiofilm Formation EnzymesIndoleamine 2 3 Dioxygenase IDOBacterial TryptophanaseLPS Biosynthesis EnzymesBacterial Amyloids Curli