Comparative evidence
Compare conditions
Put two canonical disease records side by side. The result is a shareable, deterministic comparison of what is shared, what is unique, and how much evidence each record currently carries.
- 19%
- weighted overlap
- 19
- shared signals
Comparison
Long COVIDandCrohn's Disease
0 references occur in both reconciled evidence sets. Shared signals do not establish shared causes, diagnoses, or treatments.
- 18
- Long COVID references
- 25
- Crohn's Disease references
- 0
- shared references
Metals depleted or redistributed
2 sharedTaxa enriched
5 sharedTaxa depleted
5 sharedShared
Only in Long COVID
Only in Crohn's Disease
Host response elevated
2 sharedShared
Only in Long COVID
IL 6TNF-alpha (Tumor Necrosis Factor Alpha)IL-1beta (Interleukin-1 Beta)IFN-gamma (Interferon Gamma)LPS In CirculationPD 1 On CD8TIM 3 On CD8AutoantibodiesZinc In Secretions
Only in Crohn's Disease
Host response depleted
1 sharedShared
Only in Long COVID
Only in Crohn's Disease
Anti Inflammatory CytokinesAlpha Defensins
Ecological state
2 sharedShared
Barrier DysfunctionSCFA Depletion
Only in Long COVID
Self Perpetuating Dysbiosis LoopAnaerobe To Aerobe ShiftSCFA CollapseBacterial Translocation EndotoxemiaGut Lung Axis DisruptionGut Brain Axis DisruptionTryptophan AhR DysmetabolismVirome Co DysbiosisMulti Kingdom DysbiosisNon Linear Recovery TrajectoryStrain Level Diversity CollapseEstrobolome DysfunctionUremic Metabolite AccumulationHypoxia CellularAerobe BloomBacterial TranslocationMulti Kingdom Co DysbiosisNon Linear Recovery
Only in Crohn's Disease
Leaky GutHypoxiaBiofilmBile Acid DysmetabolismTryptophan DepletionFermentative MetabolismFerroptosisButyrate CollapseNOD2 Paneth Cell Defect
Virulence and functional enzymes
1 sharedShared
Only in Long COVID
LPS Synthesis TransportAdhesion Invasion FactorsBile Salt Hydrolase (BSH)Beta-GlucuronidasePolysaccharide DegradationLPS Biosynthesis EnzymesBeta Lactamases
Only in Crohn's Disease
Zinc-MetalloproteaseIron Dependent HydrogenaseCobalt Dependent EnzymesCopper Resistance DeterminantsMucin Degrading EnzymesSiderophores EnterobactinSiderophores YersiniabactinSiderophores AerobactinZinc Metalloprotease BFTFimH AdhesinOuter Membrane VesiclesNickel-Urease