Comparative evidence

Compare conditions

Put two canonical disease records side by side. The result is a shareable, deterministic comparison of what is shared, what is unique, and how much evidence each record currently carries.

14%: weighted overlap
12: shared signals

First condition

Second condition

Comparison

Gastric CancerandColorectal Cancer

1 references occur in both reconciled evidence sets. Shared signals do not establish shared causes, diagnoses, or treatments.

7: Gastric Cancer references
36: Colorectal Cancer references
1: shared references

Metals elevated or accumulated

3 shared

Shared

Nickel Cadmium Lead

Only in Gastric Cancer

Iron Luminal

Only in Colorectal Cancer

Iron Zinc Copper Arsenic Chromium

Metals depleted or redistributed

1 shared

Taxa enriched

2 shared

Shared

Fusobacterium nucleatum Escherichia coli

Only in Gastric Cancer

Helicobacter pylori Streptococcus Prevotella

Only in Colorectal Cancer

Fusobacterium varium Bacteroides fragilis Parvimonas micra Peptostreptococcus stomatis Clostridium symbiosum Porphyromonas gingivalis Akkermansia muciniphila Candida albicans Peptostreptococcus anaerobius Enterococcus faecalis Streptococcus gallolyticus Saccharomyces cerevisiae

Taxa depleted

2 shared

Shared

Lactobacillus Faecalibacterium prausnitzii

Only in Gastric Cancer

None indexed

Only in Colorectal Cancer

Lachnospiraceae Roseburia Prevotella copri Ruminococcus albus Dialister Bifidobacterium Ruminococcus

Host response elevated

2 shared

Shared

Hepcidin Calprotectin (S100A8/A9)

Only in Gastric Cancer

Lactoferrin

Only in Colorectal Cancer

IL 6TNF-alpha (Tumor Necrosis Factor Alpha)IL-1beta (Interleukin-1 Beta)Lipopolysaccharide Lipocalin-2

Host response depleted

1 shared

Shared

Glutathione (GSH)

Only in Gastric Cancer

SeleniumGastric Acid

Only in Colorectal Cancer

IL-10 (Interleukin-10)IgATreg CellsSelenium Dependent Glutathione Peroxidase

Ecological state

0 shared

Shared

None indexed

Only in Gastric Cancer

Acid Barrier LossNickel Dependent ColonizationNitrosamine ProductionCorrea Cascade ProgressionOpened Niche ColonizationChronic NF KB Inflammation

Only in Colorectal Cancer

Hypoxia BiofilmSecondary Bile Acid AccumulationFermentative Acidic MicroenvironmentEpithelial Barrier DisruptionColonic Serotonin DepletionAnaerobic DominanceSecondary Bile Acid ExcessSCFA DepletionWarburg EffectCross Kingdom DysbiosisVirome Network Disruption

Virulence and functional enzymes

1 shared

Shared

Siderophores

Only in Gastric Cancer

Nickel-Urease NiFe-HydrogenaseCagA T4SS OncoproteinBacterial Nitrate Reductases

Only in Colorectal Cancer

FadAFap2LPS TLR4BFT ToxinColibactin PksUrease Glyoxalase I Beta-GlucuronidaseBFT Zinc MetalloproteaseColibactin GenotoxinFadA AdhesinFap2 LectinNAD(P)H Oxidase