Comparative evidence

Compare conditions

Put two canonical disease records side by side. The result is a shareable, deterministic comparison of what is shared, what is unique, and how much evidence each record currently carries.

12%: weighted overlap
9: shared signals

First condition

Second condition

Comparison

FibromyalgiaandHashimoto's Thyroiditis

0 references occur in both reconciled evidence sets. Shared signals do not establish shared causes, diagnoses, or treatments.

9: Fibromyalgia references
17: Hashimoto's Thyroiditis references
0: shared references

Metals elevated or accumulated

1 shared

Shared

Copper

Only in Fibromyalgia

None indexed

Only in Hashimoto's Thyroiditis

Iodine ExcessCadmium Lead Mercury Nickel

Metals depleted or redistributed

2 shared

Taxa enriched

0 shared

Shared

None indexed

Only in Fibromyalgia

Eggerthella Flavonifractor Coprococcus Streptococcus Collinsella Eggerthella lentaCoprococcus 2

Only in Hashimoto's Thyroiditis

Proteobacteria (Pseudomonadota)Actinobacteria (Actinomycetota)Blautia Dorea Prevotella Akkermansia muciniphila Bifidobacterium Intestinimonas Turicibacter Klebsiella pneumoniae

Taxa depleted

4 shared

Shared

Faecalibacterium prausnitzii Bifidobacterium Lachnospiraceae Roseburia

Only in Fibromyalgia

Bacteroides vulgatus Bacteroides uniformis

Only in Hashimoto's Thyroiditis

Lactobacillus Akkermansia muciniphila Coprococcus

Host response elevated

1 shared

Shared

Ceruloplasmin

Only in Fibromyalgia

Pro Inflammatory CytokinesCopperSerum ButyrateTNF-alpha (Tumor Necrosis Factor Alpha)IL 6

Only in Hashimoto's Thyroiditis

Calprotectin (S100A8/A9)HepcidinAdvanced Glycation End Products

Host response depleted

0 shared

Shared

None indexed

Only in Fibromyalgia

Glutathione (GSH)GPX3Ferritin Iron SeleniumGlutathione Peroxidase 3Serotonin

Only in Hashimoto's Thyroiditis

Selenium Dependent GPxSelenium Dependent TrxRButyrateValeric AcidGlutathione PeroxidaseThioredoxin ReductaseSelenium Dependent Selenoproteins

Ecological state

1 shared

Shared

SCFA Depletion

Only in Fibromyalgia

Butyrate ParadoxBarrier DysfunctionTryptophan Kynurenine ShuntingCopper Iron Axis ImbalanceCentral SensitizationGut Barrier Dysfunction

Only in Hashimoto's Thyroiditis

Molecular MimicryIodine Driven DysbiosisTh17 Treg ImbalanceTryptophan Metabolism DisruptionBile Acid DysmetabolismButyrate DepletionOxidative Stress

Virulence and functional enzymes

0 shared

Shared

None indexed

Only in Fibromyalgia

TryptophanasePro Inflammatory Metabolite SynthesisCopper Dependent OxidasesIndoleamine 2 3 DioxygenaseLPS BiosynthesisNeurotoxic Metabolite Production

Only in Hashimoto's Thyroiditis

Bacterial DeiodinasesBeta-GlucuronidaseLPS EndotoxinIDO1 Kynurenine AhR PathwayThyroid Peroxidase Mimics