Comparative evidence

Compare conditions

Put two canonical disease records side by side. The result is a shareable, deterministic comparison of what is shared, what is unique, and how much evidence each record currently carries.

15%: weighted overlap
10: shared signals

First condition

Second condition

Comparison

EpilepsyandHashimoto's Thyroiditis

0 references occur in both reconciled evidence sets. Shared signals do not establish shared causes, diagnoses, or treatments.

9: Epilepsy references
17: Hashimoto's Thyroiditis references
0: shared references

Metals elevated or accumulated

1 shared

Metals depleted or redistributed

2 shared

Shared

Iron Zinc

Only in Epilepsy

Magnesium

Only in Hashimoto's Thyroiditis

Selenium

Taxa enriched

2 shared

Shared

Akkermansia muciniphila Prevotella

Only in Epilepsy

Streptococcus Enterococcus Veillonella

Only in Hashimoto's Thyroiditis

Proteobacteria (Pseudomonadota)Actinobacteria (Actinomycetota)Blautia Dorea Bifidobacterium Intestinimonas Turicibacter Klebsiella pneumoniae

Taxa depleted

2 shared

Shared

Faecalibacterium prausnitzii Roseburia

Only in Epilepsy

Bacteroides Blautia Bacteroides fragilis

Only in Hashimoto's Thyroiditis

Bifidobacterium Lactobacillus Akkermansia muciniphila Lachnospiraceae Coprococcus

Host response elevated

1 shared

Shared

Calprotectin (S100A8/A9)

Only in Epilepsy

IL-1beta (Interleukin-1 Beta)IL 6TNF-alpha (Tumor Necrosis Factor Alpha)

Only in Hashimoto's Thyroiditis

Hepcidin CeruloplasminAdvanced Glycation End Products

Host response depleted

1 shared

Shared

Butyrate

Only in Epilepsy

GABA (Gamma-Aminobutyric Acid)

Only in Hashimoto's Thyroiditis

Selenium Dependent GPxSelenium Dependent TrxRValeric AcidGlutathione PeroxidaseThioredoxin ReductaseSelenium Dependent Selenoproteins

Ecological state

1 shared

Shared

SCFA Depletion

Only in Epilepsy

Oral Gut TranslocationMucin DegradationKynurenine Pathway ShuntingNeuroinflammation

Only in Hashimoto's Thyroiditis

Molecular MimicryIodine Driven DysbiosisTh17 Treg ImbalanceTryptophan Metabolism DisruptionBile Acid DysmetabolismButyrate DepletionOxidative Stress

Virulence and functional enzymes

0 shared

Shared

None indexed

Only in Epilepsy

Beta GlucosidaseTryptophanaseIndoleamine 2 3 Dioxygenase Upregulation

Only in Hashimoto's Thyroiditis

Bacterial DeiodinasesBeta-GlucuronidaseLPS EndotoxinIDO1 Kynurenine AhR PathwayThyroid Peroxidase Mimics