Comparative evidence
Compare conditions
Put two canonical disease records side by side. The result is a shareable, deterministic comparison of what is shared, what is unique, and how much evidence each record currently carries.
- 15%
- weighted overlap
- 12
- shared signals
Comparison
DepressionandUlcerative Colitis
2 references occur in both reconciled evidence sets. Shared signals do not establish shared causes, diagnoses, or treatments.
- 38
- Depression references
- 6
- Ulcerative Colitis references
- 2
- shared references
Metals depleted or redistributed
2 sharedTaxa enriched
1 sharedShared
Only in Depression
Only in Ulcerative Colitis
Taxa depleted
2 sharedShared
Only in Depression
Only in Ulcerative Colitis
Host response elevated
3 sharedHost response depleted
3 sharedShared
Only in Depression
Only in Ulcerative Colitis
None indexed
Ecological state
0 sharedShared
None indexed
Only in Depression
DysbiosisLeaky GutIntestinal PermeabilityEndotoxemiaLow SCFA ProductionImpaired Tryptophan MetabolismReduced Indole ProductionHPA Axis DysregulationTryptophan Shunting IDOSCFA DepletionHPA Axis HyperactivationBlood Brain Barrier DisruptionNeuroinflammation
Only in Ulcerative Colitis
Iron Pathobiont Feedback LoopButyrate DepletionMucosal UlcerationBarrier DysfunctionTh17 Treg ImbalanceMucin Degradation
Virulence and functional enzymes
0 sharedShared
None indexed
Only in Depression
TryptophanaseBeta-GlucuronidaseLPS BiosynthesisPro Inflammatory Metabolite SynthesisBiofilm Formation EnzymesIndoleamine 2 3 Dioxygenase IDOBacterial TryptophanaseLPS Biosynthesis EnzymesBacterial Amyloids Curli