Comparative evidence
Compare conditions
Put two canonical disease records side by side. The result is a shareable, deterministic comparison of what is shared, what is unique, and how much evidence each record currently carries.
- 19%
- weighted overlap
- 13
- shared signals
Comparison
DepressionandRheumatoid Arthritis
0 references occur in both reconciled evidence sets. Shared signals do not establish shared causes, diagnoses, or treatments.
- 38
- Depression references
- 7
- Rheumatoid Arthritis references
- 0
- shared references
Metals depleted or redistributed
0 sharedTaxa enriched
2 sharedShared
Only in Depression
Only in Rheumatoid Arthritis
Taxa depleted
3 sharedShared
Only in Depression
Only in Rheumatoid Arthritis
Host response elevated
3 sharedHost response depleted
1 sharedEcological state
0 sharedShared
None indexed
Only in Depression
DysbiosisLeaky GutIntestinal PermeabilityEndotoxemiaLow SCFA ProductionImpaired Tryptophan MetabolismReduced Indole ProductionHPA Axis DysregulationTryptophan Shunting IDOSCFA DepletionHPA Axis HyperactivationBlood Brain Barrier DisruptionNeuroinflammation
Only in Rheumatoid Arthritis
Mucosal Origin AutoimmunityBarrier DysfunctionMolecular MimicryTh17 DominanceMetal VitD Bone AxisSoil Food Chain Exposure
Virulence and functional enzymes
1 sharedShared
LPS Biosynthesis Enzymes
Only in Depression
TryptophanaseBeta-GlucuronidaseLPS BiosynthesisPro Inflammatory Metabolite SynthesisBiofilm Formation EnzymesIndoleamine 2 3 Dioxygenase IDOBacterial TryptophanaseBacterial Amyloids Curli
Only in Rheumatoid Arthritis
MetalloproteinasesSiderophores