Comparative evidence
Compare conditions
Put two canonical disease records side by side. The result is a shareable, deterministic comparison of what is shared, what is unique, and how much evidence each record currently carries.
- 21%
- weighted overlap
- 13
- shared signals
Comparison
DepressionandAnxiety Disorders
3 references occur in both reconciled evidence sets. Shared signals do not establish shared causes, diagnoses, or treatments.
- 38
- Depression references
- 12
- Anxiety Disorders references
- 3
- shared references
Metals depleted or redistributed
3 sharedTaxa enriched
1 sharedShared
Only in Depression
Only in Anxiety Disorders
Taxa depleted
4 sharedShared
Only in Depression
Only in Anxiety Disorders
Host response elevated
0 sharedShared
None indexed
Only in Depression
Only in Anxiety Disorders
Host response depleted
0 sharedShared
None indexed
Only in Depression
Only in Anxiety Disorders
Ecological state
2 sharedShared
HPA Axis DysregulationSCFA Depletion
Only in Depression
DysbiosisLeaky GutIntestinal PermeabilityEndotoxemiaLow SCFA ProductionImpaired Tryptophan MetabolismReduced Indole ProductionTryptophan Shunting IDOHPA Axis HyperactivationBlood Brain Barrier DisruptionNeuroinflammation
Only in Anxiety Disorders
Virulence and functional enzymes
2 sharedShared
TryptophanaseLPS Biosynthesis Enzymes
Only in Depression
Beta-GlucuronidaseLPS BiosynthesisPro Inflammatory Metabolite SynthesisBiofilm Formation EnzymesIndoleamine 2 3 Dioxygenase IDOBacterial TryptophanaseBacterial Amyloids Curli
Only in Anxiety Disorders
Indoleamine 2 3 Dioxygenase