Comparative evidence
Compare conditions
Put two canonical disease records side by side. The result is a shareable, deterministic comparison of what is shared, what is unique, and how much evidence each record currently carries.
- 23%
- weighted overlap
- 22
- shared signals
Comparison
Crohn's DiseaseandType 2 Diabetes
0 references occur in both reconciled evidence sets. Shared signals do not establish shared causes, diagnoses, or treatments.
- 25
- Crohn's Disease references
- 30
- Type 2 Diabetes references
- 0
- shared references
Metals depleted or redistributed
3 sharedTaxa enriched
4 sharedTaxa depleted
4 sharedShared
Only in Crohn's Disease
Only in Type 2 Diabetes
Host response elevated
2 sharedShared
Only in Crohn's Disease
Only in Type 2 Diabetes
Host response depleted
1 sharedEcological state
2 sharedShared
SCFA DepletionBile Acid Dysmetabolism
Only in Crohn's Disease
Barrier DysfunctionLeaky GutHypoxiaBiofilmTryptophan DepletionFermentative MetabolismFerroptosisButyrate CollapseNOD2 Paneth Cell Defect
Only in Type 2 Diabetes
DysbiosisLPS ElevationImpaired Intestinal BarrierLipid PeroxidationReduced Microbial DiversityEndotoxemiaGut Barrier DisruptionBile Acid DysregulationIron Overload Oxidative StressFungal Overgrowth
Virulence and functional enzymes
2 sharedShared
Only in Crohn's Disease
Zinc-MetalloproteaseIron Dependent HydrogenaseCobalt Dependent EnzymesCopper Resistance DeterminantsMucin Degrading EnzymesSiderophores EnterobactinSiderophores YersiniabactinSiderophores AerobactinZinc Metalloprotease BFTFimH AdhesinOuter Membrane Vesicles
Only in Type 2 Diabetes
LipopolysaccharideCholine TMA LyaseBile Acid DehydrataseCarbohydrate Fermentation EnzymesLPS Biosynthesis EnzymesTMA Lyase CutC CutD