Comparative evidence

Compare conditions

Put two canonical disease records side by side. The result is a shareable, deterministic comparison of what is shared, what is unique, and how much evidence each record currently carries.

16%: weighted overlap
12: shared signals

First condition

Second condition

Comparison

Ulcerative ColitisandHashimoto's Thyroiditis

2 references occur in both reconciled evidence sets. Shared signals do not establish shared causes, diagnoses, or treatments.

6: Ulcerative Colitis references
17: Hashimoto's Thyroiditis references
2: shared references

Metals elevated or accumulated

1 shared

Shared

Copper

Only in Ulcerative Colitis

Iron LuminalThallium

Only in Hashimoto's Thyroiditis

Iodine ExcessCadmium Lead Mercury Nickel

Metals depleted or redistributed

2 shared

Shared

Zinc Selenium

Only in Ulcerative Colitis

Iron SystemicManganese

Only in Hashimoto's Thyroiditis

Iron

Taxa enriched

0 shared

Shared

None indexed

Only in Ulcerative Colitis

Escherichia coli Enterococcus Fusobacterium nucleatum Ruminococcus gnavus

Only in Hashimoto's Thyroiditis

Proteobacteria (Pseudomonadota)Actinobacteria (Actinomycetota)Blautia Dorea Prevotella Akkermansia muciniphila Bifidobacterium Intestinimonas Turicibacter Klebsiella pneumoniae

Taxa depleted

3 shared

Host response elevated

3 shared

Shared

Calprotectin (S100A8/A9)Hepcidin Ceruloplasmin

Only in Ulcerative Colitis

Lactoferrin Copper

Only in Hashimoto's Thyroiditis

Advanced Glycation End Products

Host response depleted

1 shared

Shared

Glutathione Peroxidase

Only in Ulcerative Colitis

Zinc Selenium

Only in Hashimoto's Thyroiditis

Selenium Dependent GPxSelenium Dependent TrxRButyrateValeric AcidThioredoxin ReductaseSelenium Dependent Selenoproteins

Ecological state

2 shared

Shared

Butyrate DepletionTh17 Treg Imbalance

Only in Ulcerative Colitis

Iron Pathobiont Feedback LoopMucosal UlcerationBarrier DysfunctionMucin Degradation

Only in Hashimoto's Thyroiditis

Molecular MimicryIodine Driven DysbiosisSCFA DepletionTryptophan Metabolism DisruptionBile Acid DysmetabolismOxidative Stress

Virulence and functional enzymes

0 shared

Shared

None indexed

Only in Ulcerative Colitis

SiderophoresIron Acquisition SystemsAdhesinsMucin Degrading Glycosidases

Only in Hashimoto's Thyroiditis

Bacterial DeiodinasesBeta-GlucuronidaseLPS EndotoxinIDO1 Kynurenine AhR PathwayThyroid Peroxidase Mimics