Comparative evidence

Compare conditions

Put two canonical disease records side by side. The result is a shareable, deterministic comparison of what is shared, what is unique, and how much evidence each record currently carries.

16%: weighted overlap
12: shared signals

First condition

Second condition

Comparison

ObesityandInflammatory Bowel Disease (IBD)

0 references occur in both reconciled evidence sets. Shared signals do not establish shared causes, diagnoses, or treatments.

31: Obesity references
19: Inflammatory Bowel Disease (IBD) references
0: shared references

Metals elevated or accumulated

0 shared

Shared

None indexed

Only in Obesity

Cadmium Nickel Lead Manganese Zinc Iron

Only in Inflammatory Bowel Disease (IBD)

Iron MucosalCopper

Metals depleted or redistributed

1 shared

Taxa enriched

2 shared

Shared

Escherichia coli Enterobacteriaceae

Only in Obesity

Streptococcus Fusobacterium Bacteroides fragilis

Only in Inflammatory Bowel Disease (IBD)

Fusobacterium nucleatum Ruminococcus gnavus

Taxa depleted

3 shared

Shared

Faecalibacterium prausnitzii Roseburia Bifidobacterium

Only in Obesity

Lachnospiraceae Akkermansia muciniphila Oscillospiraceae

Only in Inflammatory Bowel Disease (IBD)

Blautia Lachnospiraceae (Family)Prevotella

Host response elevated

4 shared

Shared

Hepcidin Calprotectin (S100A8/A9)Lipocalin-2 Lactoferrin

Only in Obesity

Transferrin Ferritin

Only in Inflammatory Bowel Disease (IBD)

None indexed

Host response depleted

1 shared

Shared

Glutathione (GSH)

Only in Obesity

Butyrate Short-Chain Fatty Acids (SCFAs)

Only in Inflammatory Bowel Disease (IBD)

Alpha Defensins

Ecological state

0 shared

Shared

None indexed

Only in Obesity

HypoxiaMetal Driven DysbiosisReduced SCFA ProductionIncreased LPSEndotoxemiaIntestinal Permeability IncreaseFermentative Metabolism Acidic MicroenvironmentMetabolic EndotoxemiaReduced Microbial DiversityIncreased Energy HarvestBile Acid DysregulationVirome Depletion

Only in Inflammatory Bowel Disease (IBD)

Butyrate CollapseBarrier DysfunctionFerroptosisFirmicutes Bacteroidetes Ratio ShiftLPS TranslocationTMAO Elevation

Virulence and functional enzymes

1 shared

Shared

Siderophores

Only in Obesity

TMA LyaseNickel-UreaseNickel HydrogenaseZinc MetalloproteasesLPS BiosynthesisBeta-Glucuronidase

Only in Inflammatory Bowel Disease (IBD)

FimH AdhesinOuter Membrane VesiclesZinc Metalloprotease BFTMucinase