Comparative evidence
Compare conditions
Put two canonical disease records side by side. The result is a shareable, deterministic comparison of what is shared, what is unique, and how much evidence each record currently carries.
- 14%
- weighted overlap
- 10
- shared signals
Comparison
Celiac DiseaseandAutism Spectrum Disorder
1 references occur in both reconciled evidence sets. Shared signals do not establish shared causes, diagnoses, or treatments.
- 8
- Celiac Disease references
- 32
- Autism Spectrum Disorder references
- 1
- shared references
Metals depleted or redistributed
3 sharedTaxa enriched
0 sharedShared
None indexed
Only in Celiac Disease
Only in Autism Spectrum Disorder
Taxa depleted
4 sharedShared
Only in Celiac Disease
Only in Autism Spectrum Disorder
Host response elevated
0 sharedShared
None indexed
Only in Celiac Disease
Only in Autism Spectrum Disorder
Calprotectin (S100A8/A9)LactoferrinTransferrinHepcidinLipocalin-2TNF-alpha (Tumor Necrosis Factor Alpha)IL 1IL 6IL 2IL-17 (Interleukin-17)IFN-gamma (Interferon Gamma)NF KappaBMalondialdehydeFolate Receptor AutoantibodiesPropionic AcidMetallothionein InducedInflammatory Cytokines
Host response depleted
1 sharedShared
Only in Celiac Disease
None indexed
Only in Autism Spectrum Disorder
SulfateZincIL-10 (Interleukin-10)TGF-beta (Transforming Growth Factor Beta)NRF2 FunctionZO 1ClaudinsOccludinZinc MetalloenzymesGPx ActivityCu Zn SOD
Ecological state
0 sharedShared
None indexed
Only in Celiac Disease
Villous AtrophyIncreased Intestinal PermeabilityGluten Mediated Tight Junction DisassemblyNickel Allergic Contact Mucositis
Only in Autism Spectrum Disorder
Gut Barrier DysfunctionPropionic Acid NeurotoxicityOxidative StressBBB DisruptionDemyelinationExcitatory Inhibitory ImbalanceOne Carbon Metabolism DisruptionSulfate DepletionEarly Antibiotic DisruptionMaternal Microbiome TransmissionMicrobial Zinc CompetitionMetal Profile Not Single MetalGut Barrier DisruptionMis-MetallationPropionic Acid ElevationSCFA ImbalanceNeuroinflammationDevelopmental Vulnerability
Virulence and functional enzymes
1 sharedShared
Only in Celiac Disease
Bacterial ProteasesTissue Transglutaminase 2 Mimicry
Only in Autism Spectrum Disorder
ALA Dehydrase Inhibited By PbCNPase Inhibited By PbHydrogen Sulfide ProductionPropionic Acid Production