Comparative evidence
Compare conditions
Put two canonical disease records side by side. The result is a shareable, deterministic comparison of what is shared, what is unique, and how much evidence each record currently carries.
- 10%
- weighted overlap
- 7
- shared signals
Comparison
Ulcerative ColitisandNecrotizing Enterocolitis
0 references occur in both reconciled evidence sets. Shared signals do not establish shared causes, diagnoses, or treatments.
- 6
- Ulcerative Colitis references
- 19
- Necrotizing Enterocolitis references
- 0
- shared references
Metals depleted or redistributed
1 sharedTaxa enriched
2 sharedShared
Only in Ulcerative Colitis
Only in Necrotizing Enterocolitis
KlebsiellaClostridium perfringensStaphylococcusKlebsiella pneumoniaeClostridium Perfringens (Toxigenic)Sphingomonas Spp.Clostridium Spp. (Obligate Anaerobe Cluster)Bacteroides/Prevotella (Obligate Anaerobe Cluster)Staphylococcus epidermidis
Taxa depleted
1 sharedShared
Only in Ulcerative Colitis
Only in Necrotizing Enterocolitis
Host response elevated
1 sharedShared
Only in Ulcerative Colitis
Only in Necrotizing Enterocolitis
Lactoferrin EndogenousPro Inflammatory CytokinesTLR4 ExpressionLPSTNF-alpha (Tumor Necrosis Factor Alpha)IL-1beta (Interleukin-1 Beta)IL 6
Host response depleted
1 sharedEcological state
0 sharedShared
None indexed
Only in Ulcerative Colitis
Iron Pathobiont Feedback LoopButyrate DepletionMucosal UlcerationBarrier DysfunctionTh17 Treg ImbalanceMucin Degradation
Only in Necrotizing Enterocolitis
Proteobacteria Bloom 2 Weeks Pre DiagnosisVirome Convergence 10 Days Pre OnsetTLR4 Upregulation In Premature EpitheliumBifidobacterium Absence As PreconditionHMO Mediated Colonization ResistanceFeed Forward Barrier DestructionProteobacteria BloomTLR4 Feed Forward LoopVirome ConvergenceImmature BarrierParenteral Iron OverloadBiofilmBile Acid Accumulation ASBT UpregulationMuc2 Depletion Mucosal Barrier FailureObligate Anaerobe Mucosal InvasionGut Brain Axis NDI RiskAntibiotic Driven Richness Nadir Week4
Virulence and functional enzymes
1 sharedShared
Only in Ulcerative Colitis
Iron Acquisition SystemsAdhesinsMucin Degrading Glycosidases
Only in Necrotizing Enterocolitis
LPS BiosynthesisAlpha ToxinPerfringolysin OBiofilm Formation Enzymes