Comparative evidence
Compare conditions
Put two canonical disease records side by side. The result is a shareable, deterministic comparison of what is shared, what is unique, and how much evidence each record currently carries.
- 8%
- weighted overlap
- 5
- shared signals
Comparison
Irritable Bowel Syndrome (IBS)andAutism Spectrum Disorder
1 references occur in both reconciled evidence sets. Shared signals do not establish shared causes, diagnoses, or treatments.
- 7
- Irritable Bowel Syndrome (IBS) references
- 32
- Autism Spectrum Disorder references
- 1
- shared references
Metals depleted or redistributed
1 sharedShared
Only in Irritable Bowel Syndrome (IBS)
None indexed
Only in Autism Spectrum Disorder
Taxa enriched
0 sharedShared
None indexed
Only in Irritable Bowel Syndrome (IBS)
Only in Autism Spectrum Disorder
Taxa depleted
3 sharedShared
Only in Irritable Bowel Syndrome (IBS)
None indexed
Only in Autism Spectrum Disorder
Host response elevated
0 sharedShared
None indexed
Only in Irritable Bowel Syndrome (IBS)
Only in Autism Spectrum Disorder
Calprotectin (S100A8/A9)LactoferrinTransferrinHepcidinLipocalin-2TNF-alpha (Tumor Necrosis Factor Alpha)IL 1IL 6IL 2IL-17 (Interleukin-17)IFN-gamma (Interferon Gamma)NF KappaBMalondialdehydeFolate Receptor AutoantibodiesPropionic AcidMetallothionein InducedInflammatory Cytokines
Host response depleted
0 sharedShared
None indexed
Only in Irritable Bowel Syndrome (IBS)
Zinc Dependent Defensins
Only in Autism Spectrum Disorder
Glutathione (GSH)SulfateZincIL-10 (Interleukin-10)TGF-beta (Transforming Growth Factor Beta)NRF2 FunctionZO 1ClaudinsOccludinZinc MetalloenzymesGPx ActivityCu Zn SOD
Ecological state
0 sharedShared
None indexed
Only in Irritable Bowel Syndrome (IBS)
Nickel Allergic Contact MucositisMast Cell Nerve AxisSIBOVisceral HypersensitivityFermentative DysbiosisBarrier Dysfunction
Only in Autism Spectrum Disorder
Gut Barrier DysfunctionPropionic Acid NeurotoxicityOxidative StressBBB DisruptionDemyelinationExcitatory Inhibitory ImbalanceOne Carbon Metabolism DisruptionSulfate DepletionEarly Antibiotic DisruptionMaternal Microbiome TransmissionMicrobial Zinc CompetitionMetal Profile Not Single MetalGut Barrier DisruptionMis-MetallationPropionic Acid ElevationSCFA ImbalanceNeuroinflammationDevelopmental Vulnerability
Virulence and functional enzymes
0 sharedShared
None indexed
Only in Irritable Bowel Syndrome (IBS)
TLR4 Nickel ActivationMast Cell Degranulation Mediators
Only in Autism Spectrum Disorder
Beta-GlucuronidaseALA Dehydrase Inhibited By PbCNPase Inhibited By PbHydrogen Sulfide ProductionPropionic Acid Production