Comparative evidence
Compare conditions
Put two canonical disease records side by side. The result is a shareable, deterministic comparison of what is shared, what is unique, and how much evidence each record currently carries.
- 9%
- weighted overlap
- 5
- shared signals
Comparison
DepressionandIrritable Bowel Syndrome (IBS)
2 references occur in both reconciled evidence sets. Shared signals do not establish shared causes, diagnoses, or treatments.
- 38
- Depression references
- 7
- Irritable Bowel Syndrome (IBS) references
- 2
- shared references
Metals depleted or redistributed
1 sharedTaxa enriched
1 sharedShared
Only in Depression
Only in Irritable Bowel Syndrome (IBS)
Taxa depleted
3 sharedShared
Only in Depression
Only in Irritable Bowel Syndrome (IBS)
None indexed
Host response elevated
0 sharedShared
None indexed
Only in Depression
Only in Irritable Bowel Syndrome (IBS)
Host response depleted
0 sharedShared
None indexed
Only in Depression
Only in Irritable Bowel Syndrome (IBS)
Zinc Dependent Defensins
Ecological state
0 sharedShared
None indexed
Only in Depression
DysbiosisLeaky GutIntestinal PermeabilityEndotoxemiaLow SCFA ProductionImpaired Tryptophan MetabolismReduced Indole ProductionHPA Axis DysregulationTryptophan Shunting IDOSCFA DepletionHPA Axis HyperactivationBlood Brain Barrier DisruptionNeuroinflammation
Only in Irritable Bowel Syndrome (IBS)
Nickel Allergic Contact MucositisMast Cell Nerve AxisSIBOVisceral HypersensitivityFermentative DysbiosisBarrier Dysfunction
Virulence and functional enzymes
0 sharedShared
None indexed
Only in Depression
TryptophanaseBeta-GlucuronidaseLPS BiosynthesisPro Inflammatory Metabolite SynthesisBiofilm Formation EnzymesIndoleamine 2 3 Dioxygenase IDOBacterial TryptophanaseLPS Biosynthesis EnzymesBacterial Amyloids Curli
Only in Irritable Bowel Syndrome (IBS)
TLR4 Nickel ActivationMast Cell Degranulation Mediators