Comparative evidence
Compare conditions
Put two canonical disease records side by side. The result is a shareable, deterministic comparison of what is shared, what is unique, and how much evidence each record currently carries.
- 9%
- weighted overlap
- 6
- shared signals
Comparison
DepressionandBarrett's Esophagus
0 references occur in both reconciled evidence sets. Shared signals do not establish shared causes, diagnoses, or treatments.
- 38
- Depression references
- 7
- Barrett's Esophagus references
- 0
- shared references
Metals depleted or redistributed
2 sharedTaxa enriched
1 sharedTaxa depleted
2 sharedShared
Only in Depression
Only in Barrett's Esophagus
Host response elevated
0 sharedShared
None indexed
Only in Depression
Only in Barrett's Esophagus
Tlr4 LigandsIl 6Nf KbLps
Host response depleted
0 sharedShared
None indexed
Only in Depression
Only in Barrett's Esophagus
Claudin 1
Ecological state
0 sharedShared
None indexed
Only in Depression
DysbiosisLeaky GutIntestinal PermeabilityEndotoxemiaLow SCFA ProductionImpaired Tryptophan MetabolismReduced Indole ProductionHPA Axis DysregulationTryptophan Shunting IDOSCFA DepletionHPA Axis HyperactivationBlood Brain Barrier DisruptionNeuroinflammation
Only in Barrett's Esophagus
Gram Negative Anaerobe DominanceType II MicrobiomeIntestinal MetaplasiaAneuploidyOral Esophageal TranslocationH Pylori Paradoxical ProtectionProgressive Prevotella Gradient
Virulence and functional enzymes
1 sharedShared
LPS Biosynthesis
Only in Depression
TryptophanaseBeta-GlucuronidasePro Inflammatory Metabolite SynthesisBiofilm Formation EnzymesIndoleamine 2 3 Dioxygenase IDOBacterial TryptophanaseLPS Biosynthesis EnzymesBacterial Amyloids Curli
Only in Barrett's Esophagus
TonB Iron TransportMlaD Membrane Lipid AsymmetryBacterial Proteases