Comparative evidence
Compare conditions
Put two canonical disease records side by side. The result is a shareable, deterministic comparison of what is shared, what is unique, and how much evidence each record currently carries.
- 18%
- weighted overlap
- 14
- shared signals
Comparison
Breast CancerandDepression
1 references occur in both reconciled evidence sets. Shared signals do not establish shared causes, diagnoses, or treatments.
- 21
- Breast Cancer references
- 38
- Depression references
- 1
- shared references
Metals depleted or redistributed
2 sharedTaxa enriched
1 sharedTaxa depleted
2 sharedShared
Only in Breast Cancer
Only in Depression
Host response elevated
2 sharedShared
Only in Breast Cancer
Only in Depression
Host response depleted
2 sharedEcological state
1 sharedShared
SCFA Depletion
Only in Breast Cancer
Estrogen RecirculationBeta Glucuronidase ActivityMetalloestrogen BurdenAlpha Diversity ReductionCross Kingdom Dysbiosis
Only in Depression
DysbiosisLeaky GutIntestinal PermeabilityEndotoxemiaLow SCFA ProductionImpaired Tryptophan MetabolismReduced Indole ProductionHPA Axis DysregulationTryptophan Shunting IDOHPA Axis HyperactivationBlood Brain Barrier DisruptionNeuroinflammation
Virulence and functional enzymes
1 sharedShared
Only in Breast Cancer
BFT Zinc MetalloproteaseFadA AdhesinFap2 LectinMMP 9
Only in Depression
TryptophanaseLPS BiosynthesisPro Inflammatory Metabolite SynthesisBiofilm Formation EnzymesIndoleamine 2 3 Dioxygenase IDOBacterial TryptophanaseLPS Biosynthesis EnzymesBacterial Amyloids Curli