Comparative evidence
Compare conditions
Put two canonical disease records side by side. The result is a shareable, deterministic comparison of what is shared, what is unique, and how much evidence each record currently carries.
- 8%
- weighted overlap
- 5
- shared signals
Comparison
Autism Spectrum DisorderandIrritable Bowel Syndrome (IBS)
1 references occur in both reconciled evidence sets. Shared signals do not establish shared causes, diagnoses, or treatments.
- 32
- Autism Spectrum Disorder references
- 7
- Irritable Bowel Syndrome (IBS) references
- 1
- shared references
Metals depleted or redistributed
1 sharedShared
Only in Autism Spectrum Disorder
Only in Irritable Bowel Syndrome (IBS)
None indexed
Taxa enriched
0 sharedShared
None indexed
Only in Autism Spectrum Disorder
Only in Irritable Bowel Syndrome (IBS)
Taxa depleted
3 sharedShared
Only in Autism Spectrum Disorder
Only in Irritable Bowel Syndrome (IBS)
None indexed
Host response elevated
0 sharedShared
None indexed
Only in Autism Spectrum Disorder
Calprotectin (S100A8/A9)LactoferrinTransferrinHepcidinLipocalin-2TNF-alpha (Tumor Necrosis Factor Alpha)IL 1IL 6IL 2IL-17 (Interleukin-17)IFN-gamma (Interferon Gamma)NF KappaBMalondialdehydeFolate Receptor AutoantibodiesPropionic AcidMetallothionein InducedInflammatory Cytokines
Only in Irritable Bowel Syndrome (IBS)
Host response depleted
0 sharedShared
None indexed
Only in Autism Spectrum Disorder
Glutathione (GSH)SulfateZincIL-10 (Interleukin-10)TGF-beta (Transforming Growth Factor Beta)NRF2 FunctionZO 1ClaudinsOccludinZinc MetalloenzymesGPx ActivityCu Zn SOD
Only in Irritable Bowel Syndrome (IBS)
Zinc Dependent Defensins
Ecological state
0 sharedShared
None indexed
Only in Autism Spectrum Disorder
Gut Barrier DysfunctionPropionic Acid NeurotoxicityOxidative StressBBB DisruptionDemyelinationExcitatory Inhibitory ImbalanceOne Carbon Metabolism DisruptionSulfate DepletionEarly Antibiotic DisruptionMaternal Microbiome TransmissionMicrobial Zinc CompetitionMetal Profile Not Single MetalGut Barrier DisruptionMis-MetallationPropionic Acid ElevationSCFA ImbalanceNeuroinflammationDevelopmental Vulnerability
Only in Irritable Bowel Syndrome (IBS)
Nickel Allergic Contact MucositisMast Cell Nerve AxisSIBOVisceral HypersensitivityFermentative DysbiosisBarrier Dysfunction
Virulence and functional enzymes
0 sharedShared
None indexed
Only in Autism Spectrum Disorder
Beta-GlucuronidaseALA Dehydrase Inhibited By PbCNPase Inhibited By PbHydrogen Sulfide ProductionPropionic Acid Production
Only in Irritable Bowel Syndrome (IBS)
TLR4 Nickel ActivationMast Cell Degranulation Mediators