Search: “metabolomics”

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A complete external heart and major vessels appear beside an artery cross-section with a restrained eccentric plaque and open lumen.

Diseases14 sources

Cardiovascular Disease

Cardiovascular disease (CVD) -- encompassing atherosclerosis, coronary artery disease, hypertension, myocardial infarction, heart failure, and stroke -- is the leading cause of death globally. The gut-heart axis has emerged as a central paradigm linking microbial metabo…

A complete large-intestine teaching model contains one open sigmoid cutaway with a small raised irregular mucosal lesion.

Diseases18 sources

Colorectal Cancer

Colorectal cancer (CRC) is the third most common cancer worldwide and the second leading cause of cancer death. Over 90% of cases are sporadic, driven by a complex interplay between genetic predisposition, dietary habits, gut microbiome composition, and environmental ex…

A complete intact brain teaching model appears beside a separate assembly of connected cortical- and limbic-like forms.

Diseases10 sources

Depression

Depression is the most prevalent mental health disorder globally, affecting over 280 million people zhu 2025 microbiota gut brain axis depression review, and one of the most metal-sensitive conditions in this wiki. It sits at the convergence of nearly every pathway cata…

A complete internal pelvic reproductive model has four small dark superficial foci, two on one ovary and two on nearby peritoneal tissue.

Diseases11 sources

Endometriosis

Endometriosis is a chronic estrogen-dependent inflammatory condition affecting approximately 10% of reproductive-age women, characterized by the growth of endometrial-like tissue outside the uterus colonetti 2023 gut vaginal microbiota endometriosis meta analysis. The c…

Three normal teaching models show a complete brain and upper spinal continuation, an unmarked spinal-cord cross-section, and an intact axon with four sheath internodes.

Diseases5 sources

Multiple Sclerosis

Multiple sclerosis (MS) is a chronic autoimmune demyelinating disease of the central nervous system, with a global prevalence of approximately 2.8 million attfield 2022 immunology ms nature review. The conventional framing centers on genetic susceptibility (HLA-DRB115:0…

Generic small-and-large-intestine anatomy appears beside two layered wall models, one with a bounded non-graphic surface defect.

Diseases18 sources

Necrotizing Enterocolitis

Necrotizing enterocolitis (NEC) is the most common and lethal gastrointestinal emergency in premature infants, affecting 5-12% of very low birth weight neonates (<1500 g) with mortality rates of 20-30%. Characterized by intestinal inflammation, necrosis, and perforation…

Three pancreatic teaching models appear separately, including one with a bounded nonspecific growth near the pancreatic head.

Diseases22 sources

Pancreatic Cancer

Pancreatic cancer is the fifth leading cause of cancer death in Western nations, with rising incidence globally. Pancreatic ductal adenocarcinoma (PDAC) accounts for over 90% of cases. Five-year survival remains approximately 12%, owing to late-stage diagnosis, aggressi…

A lateral brain, symmetric deep-brain orientation abstraction, and a connected cluster of three neuron-like cells appear separately.

Diseases14 sources

Parkinson's Disease

The second most common neurodegenerative disease, affecting over 10 million people worldwide dorsey 2018 parkinsons incidence meta analysis. Characterized by progressive loss of dopaminergic neurons in the substantia nigra, alpha-synuclein aggregation (Lewy bodies), and…