WikiBiomeThe human microbiome encyclopedia
Comparative evidence

Compare conditions

Put two canonical disease records side by side. The result is a shareable, deterministic comparison of what is shared, what is unique, and how much evidence each record currently carries.

22%
weighted overlap
17
shared signals
Comparison

Crohn's DiseaseandUlcerative Colitis

3 references occur in both reconciled evidence sets. Shared signals do not establish shared causes, diagnoses, or treatments.

25
Crohn's Disease references
6
Ulcerative Colitis references
3
shared references
02

Metals depleted or redistributed

3 shared

Shared

ZincSeleniumManganese

Only in Crohn's Disease

Zinc LuminalIron LuminalManganese LuminalCopper LuminalGlutathione (GSH)

Only in Ulcerative Colitis

Iron Systemic
06

Host response depleted

0 shared

Shared

None indexed

Only in Crohn's Disease

Glutathione (GSH)Anti Inflammatory CytokinesAlpha Defensins

Only in Ulcerative Colitis

ZincSeleniumGlutathione Peroxidase
07

Ecological state

1 shared

Shared

Barrier Dysfunction

Only in Crohn's Disease

Leaky GutHypoxiaBiofilmSCFA DepletionBile Acid DysmetabolismTryptophan DepletionFermentative MetabolismFerroptosisButyrate CollapseNOD2 Paneth Cell Defect

Only in Ulcerative Colitis

Iron Pathobiont Feedback LoopButyrate DepletionMucosal UlcerationTh17 Treg ImbalanceMucin Degradation
08

Virulence and functional enzymes

1 shared

Shared

Siderophores

Only in Crohn's Disease

Zinc-MetalloproteaseIron Dependent HydrogenaseCobalt Dependent EnzymesCopper Resistance DeterminantsMucin Degrading EnzymesSiderophores EnterobactinSiderophores YersiniabactinSiderophores AerobactinZinc Metalloprotease BFTFimH AdhesinOuter Membrane VesiclesNickel-Urease

Only in Ulcerative Colitis

Iron Acquisition SystemsAdhesinsMucin Degrading Glycosidases