WikiBiomeThe human microbiome encyclopediaRanked matches across titles, topics, categories, and article introductions, filtered to mechanism.
The collective ability of the resident gut microbiome to prevent colonization by exogenous pathogens and suppress expansion of resident pathobionts. Colonization resistance is not a property of any single organism but an emergent function of the whole microbial communit…
Every meal delivers metals to the gut lumen — essential minerals, trace elements, and contaminants alike. These metals do not passively transit the GI tract. They actively reshape the microbial ecosystem, selecting for metal-tolerant organisms, enabling virulence in met…
The transfer of processed stool from a healthy donor into a recipient's gastrointestinal tract to restore a disrupted microbial community. FMT is the most direct form of microbiome intervention -- replacing the entire community rather than supplementing individual strai…
The community of trillions of microorganisms — bacteria, archaea, fungi (mycobiome), viruses, and bacteriophages — inhabiting the human gastrointestinal tract, with the highest density in the colon (~10¹¹ cells/g). The gut microbiome encodes 100–150 times more genes tha…
Interleukin-6 is a pleiotropic cytokine that sits at the crossroads of innate immunity, adaptive immunity, and metabolism. It is one of the most frequently elevated inflammatory mediators across conditions in this wiki — appearing in disease signatures spanning IBD, aut…
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The use of gut microbiome composition, microbial metabolites, or microbial products as diagnostic, prognostic, or monitoring tools for disease. Unlike traditional clinical biomarkers, microbial biomarkers capture the functional state of the host-microbiome ecosystem and…
Non-digestible food substrates that selectively stimulate the growth and/or activity of beneficial gut microorganisms, conferring health benefits to the host. Distinct from probiotics (live organisms) and postbiotics (microbial metabolic products), prebiotics act as fue…
This knowledge-base record is being expanded from WikiBiome’s evidence graph.