Mechanisms4 sources
Acetate
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Search: “acetate”
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8 records in this view
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Microorganisms3 sources
Bifidobacterium adolescentis
Bifidobacterium adolescentis is a Gram-positive, obligate anaerobic species within the phylum Actinobacteria and the dominant Bifidobacterium species in the adult human gut. It is a specialist degrader of resistant starch and dietary fiber, producing acetate and lactate…
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Mechanisms4 sources
Cross-Feeding
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Reference0 sources
Glossary
Alphabetical definitions of specialist terms used throughout this wiki. Where a full concept page exists, the term links to it. --- AhR (aryl hydrocarbon receptor) -- A ligand-activated transcription factor that senses microbial metabolites (especially indoles from tryp…
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Mechanisms3 sources
Ketone Bodies
Ketone bodies (beta-hydroxybutyrate [BHB], acetoacetate, acetone) are produced by hepatic fatty acid oxidation during carbohydrate restriction, fasting, or ketogenic diet consumption. BHB is the most abundant and is structurally and functionally analogous to butyrate — …
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Mechanisms5 sources
Propionic Acid
A three-carbon short-chain fatty acid (SCFA) produced primarily by Bacteroidetes and certain Firmicutes through anaerobic fermentation of dietary substrates. At physiological concentrations in healthy gut microbiomes, propionic acid (PPA) is a normal fermentation produc…
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Microorganisms8 sources
Ruminococcus albus
Ruminococcus albus is a Gram-positive, obligate anaerobic bacterium that represents one of the primary cellulolytic (fiber-degrading) specialists in the human gut microbiota. This species constructs cellulosomes — extraordinary multi-enzyme complexes organized on bacter…
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Mechanisms9 sources
Short-Chain Fatty Acids (SCFAs)
The most extensively referenced missing concept in this wiki. SCFAs -- acetate (C2), propionate (C3), and butyrate (C4) -- are the primary metabolic products of anaerobic bacterial fermentation of dietary fiber in the colon. They serve as the critical molecular link bet…