Ketone Bodies

Microbiome Connection#

The Ketogenic Diet profoundly alters Gut Microbiome composition: increases Akkermansia, reduces Bifidobacterium, and shifts SCFA profiles.^{[1]Ketogenic Diet Alleviates Colitis by Reduction of Colonic Group 3 Innate Lymphoid Cells Through Altering Gut MicrobiomeKong C, Yan X, Liu Y et al. · 2021Open reference 1 ↓[2]The Impact of Ketogenic Diet on Colorectal Cancer Progression and the Co-evolution of Gut Microbiota: A Research ProtocolMelika Shirdarreh, Yasamin Sadeghi, Tina Rahimi · 2021Open reference 2 ↓}

BHB modulates intestinal ILC3 cells and IL-22 production.^{[1]Ketogenic Diet Alleviates Colitis by Reduction of Colonic Group 3 Innate Lymphoid Cells Through Altering Gut MicrobiomeKong C, Yan X, Liu Y et al. · 2021Open reference 1 ↓} Clinical applications: epilepsy (established), ASD (emerging), neurodegeneration (investigational).^{[3]Li 2021 — Ketogenic Diet and the Treatment of ASDQinrui Li, Jingjing Liang, Na Fu et al. · 2021Open reference 3 ↓}