Infection metallomics for critical care in the post-COVID era
Patil RH, Luptakova D, Havlicek V
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- Year
- 2021
- Journal
- Mass Spectrometry Reviews
- WikiBiome key
patil-2021-infection-metallomics-critical-care
Defines infection metallomics as a diagnostic platform: microbial metallophores (siderophores and Cu/Zn/Ni/Co-chelators) detected by mass spectrometry can distinguish invasive infection from colonization. Underpins WikiBiome's framing of pathogen virulence as a metal-acquisition phenomenon and establishes metallophores as signature biomarkers across sepsis, pneumonia, UTI, and CNS infection.
Criteria met: 1 · 3 · 4 · 5Used in 24 visible records
microbeAspergillus→microbeCitrobacter→metalCopper→microbeCryptococcus neoformans→metalIron→microbeKlebsiella pneumoniae→microbeMycobacterium tuberculosis→otherNeisseria Meningitidis→metalNickel→diseasePneumonia→diseaseSepsis→diseaseTuberculosis→microbeYersinia pestis→metalZinc→mechanismBiomarkers→mechanismBlood-Brain Barrier→defenseInter-Kingdom Metal Shielding→mechanismMatrix Metalloproteases (MMPs)→defenseMetal-Dependent Virulence→mechanismMetallomics→mechanismMicrobial Biomarkers→defenseMicrobial Metallomics→mechanismMycobiome→mechanismN-Glycosylation→Connect the evidence
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