Host defenses12 sources
Antimicrobial Metals
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Search: “zinc”
Ranked matches across titles, topics, categories, and article introductions, filtered to defense.
9 records in this view
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Host defenses4 sources
Calprotectin (S100A8/A9)
A heterodimer of S100A8 and S100A9 calcium-binding proteins that constitutes approximately 60% of the cytosolic protein content of neutrophils. Calprotectin is a central effector of nutritional immunity, sequestering essential transition metals from invading pathogens a…
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Host defenses6 sources
Dyshomeostasis
The pathological disruption of normal metal homeostasis — the tightly regulated balance of essential trace elements (iron, zinc, copper, manganese, selenium, cobalt) and the effective exclusion of toxic metals (cadmium, lead, mercury, arsenic). Dyshomeostasis is a conve…
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Host defenses3 sources
Metal Homeostasis
The biological processes by which organisms maintain proper intracellular and systemic concentrations of essential metals -- importing what is needed, storing excess safely, and exporting or sequestering surplus. Both host and microbial systems have evolved elaborate me…
Host defenses8 sources
Metal-Dependent Virulence
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Host defenses11 sources
Nutritional Immunity (Metal Sequestration)
The strategy by which mammalian hosts withhold essential metals from invading pathogens to limit their growth. Well-established for iron and zinc; underexplored but potentially powerful for nickel.
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Host defenses11 sources
Pathogen Metal Acquisition Systems
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Host defenses7 sources
Siderophores and Metallophores
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Host defenses12 sources
Superoxide Dismutase
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