Exposure to Cadmium and Its Impacts on Human Health: A Short Review

Comprehensively maps cadmium toxicology across organ systems—kidneys (25-30 year half-life, tubular reabsorption dynamics), lungs (4-5x elevation in smokers), neurons (voltage-gated Ca channel entry), cardiovascular (endothelial damage, atherosclerosis), placenta (embryonic gene expression disruption via methyltransferase inhibition)—establishing cadmium as a multi-system metal burden. WikiBiome depends on this evidence to explain why cadmium dysregulation appears across disease signatures and to characterize organ-specific accumulation pathways.