Exposure to Cadmium and Its Impacts on Human Health: A Short Review
Puthiyavalappil Rasin, Ashwathi A V, Sabeel M Basheer, Jebiti Haribabu, Juan F. Santibanez, Claudio Allard Garrote, Arunachalam Arulraj, Ramalinga Viswanathan Mangalaraja
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- Year
- 2025
- Journal
- Journal of Hazardous Materials Advances
- WikiBiome key
rasin-2025-cadmium-exposure-health-review
Comprehensively maps cadmium toxicology across organ systems—kidneys (25-30 year half-life, tubular reabsorption dynamics), lungs (4-5x elevation in smokers), neurons (voltage-gated Ca channel entry), cardiovascular (endothelial damage, atherosclerosis), placenta (embryonic gene expression disruption via methyltransferase inhibition)—establishing cadmium as a multi-system metal burden. WikiBiome depends on this evidence to explain why cadmium dysregulation appears across disease signatures and to characterize organ-specific accumulation pathways.
Criteria met: 2 · 3 · 4Used in 17 visible records
diseaseAlzheimer's Disease→metalCadmium→metalCalcium→diseaseCardiovascular Disease→diseaseDepression→diseaseFemale Infertility→metalNickel→diseaseParkinson's Disease→mechanismEpigenetics→defenseLipocalin-2→mechanismMetallothionein→mechanismMitochondrial Dysfunction→mechanismOxidative Stress→mechanismTryptophan→diseaseType 2 Diabetes→stopSTOP: Calcium Supplementation with Cadmium Exposure→analysisMetal-Disease Matrix: A Cross-Source Synthesis→Connect the evidence
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