Mechanisms15 sources
Iron-Sulfur Clusters
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Search: “metalloenzyme”
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Mechanisms3 sources
Metallochaperone
Specialized proteins that escort metal ions from their point of entry to specific metalloenzyme targets, ensuring correct metalation in a cytoplasm crowded with competing metal-binding sites. Metallochaperones solve a fundamental problem in metal biology: how does the r…
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Mechanisms6 sources
Urease
The most widespread nickel-dependent virulence factor across human pathogens. Urease is found in at least 40 prokaryotic and 9 eukaryotic pathogenic species, making it the single most important enzyme linking dietary/environmental nickel to infectious disease.