Mechanisms5 sources
Arachidonic Acid
This knowledge-base record is being expanded from WikiBiome’s evidence graph.
Search: “IBD”
Ranked matches across titles, topics, categories, and article introductions, filtered to mechanism.
12 records in this view
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B
Mechanisms8 sources
Bile Acid Metabolism
Bile acids are cholesterol-derived amphipathic molecules synthesized in the liver, secreted into the duodenum, and extensively modified by gut bacteria. The host-microbe co-metabolism of bile acids creates a signaling network with profound effects on lipid metabolism, g…
C
Mechanisms3 sources
Comorbidities
The co-occurrence of multiple diseases in the same individual at rates exceeding chance. Comorbidity patterns are a central puzzle in medicine -- why do IBD patients develop CVD? Why does PCOS cluster with T2D? Why do neurodegenerative diseases associate with depression…
Mechanisms4 sources
Copper Dysregulation
Perhaps the most pervasive metallomic finding across human disease: copper is elevated in nearly every pathological condition examined in this wiki -- cancer (pan-cancer), PCOS, cardiovascular disease, depression, schizophrenia, IBD, and rheumatoid arthritis. Simultaneo…
F
Mechanisms4 sources
Fecal Microbiota Transplant (FMT)
The transfer of processed stool from a healthy donor into a recipient's gastrointestinal tract to restore a disrupted microbial community. FMT is the most direct form of microbiome intervention -- replacing the entire community rather than supplementing individual strai…
G
Mechanisms3 sources
Gut-Penis Axis
This knowledge-base record is being expanded from WikiBiome’s evidence graph.
I
Mechanisms5 sources
IL-10 (Interleukin-10)
This knowledge-base record is being expanded from WikiBiome’s evidence graph.
Mechanisms4 sources
IL-17 (Interleukin-17)
This knowledge-base record is being expanded from WikiBiome’s evidence graph.
Mechanisms13 sources
Interleukin-6 (IL-6)
Interleukin-6 is a pleiotropic cytokine that sits at the crossroads of innate immunity, adaptive immunity, and metabolism. It is one of the most frequently elevated inflammatory mediators across conditions in this wiki — appearing in disease signatures spanning IBD, aut…
M
Mechanisms3 sources
Mycobiome
The fungal component of the human microbiome, comprising ~0.1-1% of the total gut microbial community by abundance but disproportionately active in immune signaling and cross-kingdom interactions. While bacterial communities dominate microbiome research, emerging eviden…
S
Mechanisms6 sources
Shotgun Metagenomics
This knowledge-base record is being expanded from WikiBiome’s evidence graph.
V
Mechanisms3 sources
Virulence Factors
This knowledge-base record is being expanded from WikiBiome’s evidence graph.