Host defenses12 sources
Antimicrobial Metals
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Host defenses5 sources
Lactoferrin
An iron-binding glycoprotein of the transferrin family that sequesters iron (and potentially other metals) from pathogens at mucosal surfaces and sites of inflammation. Lactoferrin is a key effector of nutritional immunity, complementing calprotectin's role in metal res…
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Host defenses5 sources
Siderophore Competition
Small, high-affinity iron-chelating molecules secreted by bacteria and fungi to scavenge ferric iron (Fe3+) from the environment. Siderophore competition is a fundamental ecological force in the gut microbiome: organisms with superior iron acquisition systems gain a dec…