WikiBiomeThe human microbiome encyclopediaRanked matches across titles, topics, categories, and article introductions.
Beta-lactamases are bacterial enzymes that hydrolyze the beta-lactam ring of penicillins, cephalosporins, and carbapenems, rendering them inactive. They are the most common mechanism of antibiotic resistance and a central concern in the antimicrobial resistance crisis. …
Cephalosporins are a class of beta-lactam antibiotics (five generations) that inhibit bacterial cell wall synthesis by binding penicillin-binding proteins. They are among the most prescribed antibiotic classes and among the most disruptive to the gut microbiome.
Penicillium is a genus of filamentous fungi best known as the source of penicillin. In the WikiBiome context, Penicillium appears in the gut mycobiome — the fungal component of the microbiome — with associations across ASD, pancreatitis, and cardiometabolic disease.