Kravchenko 2023 — Thyroid hormones and minerals in immunocorrection of disorders in autoimmune thyroid diseases

Maps mineral-specific immunomodulation in autoimmune thyroid disease, showing how selenium supplementation reduces TPO antibodies via selenoprotein GPx upregulation, zinc enables thymulin activation for T cell function, and iron deficiency impairs TPO activity while increasing autoimmune susceptibility. WikiBiome depends on this evidence to establish how dysbiotic organisms (depleted in metal-dependent SCFA producers) directly undermine thyroid barrier tolerance — linking metal dysbiosis to Treg dysfunction via metal-dependent enzyme failures.