Mechanisms5 sources
Indole and Indole Derivatives
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Search: “microbial-metabolite”
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I
P
Mechanisms5 sources
p-Cresol
A microbial metabolite produced by gut bacteria through tyrosine fermentation that has emerged as one of the most consistent biomarkers linking gut dysbiosis to neurological and renal disease. p-Cresol (4-methylphenol) is a simple aromatic compound, but its effects are …
Mechanisms8 sources
Polyamines
Polyamines -- putrescine, spermidine, spermine, and cadaverine -- are small polycationic molecules produced by both the host and the gut microbiome. They regulate cell growth, differentiation, apoptosis, and immune function. In the gut ecosystem, polyamines are metaboli…
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Mechanisms3 sources
Succinate
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T
Mechanisms3 sources
Tryptamine
Tryptamine is a microbial decarboxylation product of tryptophan, produced by bacterial tryptophan decarboxylase (found in ruminococcus gnavus, Clostridium sporogenes, and others). It is a serotonin receptor agonist (particularly 5-HT4) that stimulates gut motility and f…