WikiBiomeThe human microbiome encyclopediaRanked matches across titles, topics, categories, and article introductions, filtered to mechanism.
Acetate (acetic acid, C2) is the most abundant SCFA in the colon (~60% of total SCFAs) and the primary cross-feeding substrate for butyrate production. Produced by Bacteroides, Bifidobacterium, Prevotella, and acetogens from dietary fiber fermentation, acetate reaches p…
Preterm birth (<37 weeks gestation) is the leading cause of neonatal mortality and morbidity worldwide (~15 million/year). The vaginal microbiome is a key determinant of preterm birth risk — Lactobacillus-depleted vaginal communities (CST-IV, enriched in gardnerella, at…
Saccharolytic fermentation is the microbial breakdown of carbohydrates (dietary fiber, resistant starch, host glycans) to produce short chain fatty acids (acetate, propionate, butyrate) and gases (H₂, CO₂, CH₄). It is the beneficial fermentation mode — the metabolic act…
The semen microbiome refers to the microbial community inhabiting the male reproductive tract and seminal fluid. Core genera identified through shotgun metagenomic sequencing include Corynebacterium, Staphylococcus, Streptococcus, and Prevotella, though composition vari…
Succinate is a Krebs cycle intermediate and a microbial metabolite produced by dialister, Bacteroides, Prevotella, and other gut bacteria. Beyond its role in energy metabolism, succinate is a signaling molecule that activates GPR91 (SUCNR1) on immune cells and neurons, …