STOP: Iron Supplementation In ASD Dysbiosis (Without Metal Dysregulation Assessment)

Overview

> Warning: Clinical Disclaimer: This STOP page represents a hypothesis based on mechanistic evidence and should NOT replace clinical judgment. Always consult with a qualified healthcare provider before modifying any treatment plan. Evidence quality ratings reflect the strength of the mechanistic reasoning, not RCT-level clinical proof.

> Important caveat: Iron deficiency anemia in children requires medical evaluation. This STOP applies only when hepcidin is elevated (functional restriction), NOT when true iron deficiency is present. Children with genuine iron deficiency (low hepcidin, low ferritin from blood loss or malabsorption) still require appropriate iron repletion under medical supervision.

References (4)

  1. . lewandowska 2022 microbiota asd systematic review
  2. . zhuang 2024 asd pathogenesis biomarker intervention
  3. . wang 2023 microbiota gut brain axis neurodevelopmental
  4. . wang 2024 understanding autism causes diagnosis therapies