Serum Levels of Selenium, Zinc, Copper, Manganese, and Iron in Prostate Cancer Patients
Saleh A. K. Saleh, Heba M. Adly, Altaf A. Abdelkhaliq, Anmar M. Nassir
Share & cite
Links open in a new tab.
Citation record
- Year
- 2020
- Journal
- Current Urology
- WikiBiome key
saleh-2020-serum-trace-elements-prostate-cancer
Characterizes the prostate cancer metallomic signature—Se/Zn/Mn depletion paired with Cu/Fe elevation—and establishes Cu-Zn competitive antagonism at the metallothionein level as a carcinogenic mechanism. WikiBiome depends on this evidence to recognize the pan-cancer metal pattern (Cu accumulation + Zn loss) as a cross-condition marker and to understand how metal dysregulation enables malignant transformation across tissue types.
Criteria met: 1 · 3 · 4 · 5Used in 10 visible records
metalCopper→metalIron→metalManganese→metalSelenium→metalZinc→mechanismCopper Dysregulation→mechanismMetal Carcinogenesis→mechanismMetallomics→mechanismMetallothionein→analysisMetal-Disease Matrix: A Cross-Source Synthesis→Connect the evidence
Publicly readable discussion by ORCID-authenticated researchers. Questions, interpretation, methods, corrections, and new evidence stay attached to this record.
No discussion yet. Start with a precise question or a source-backed observation.
Published page changes
This record shows only material changes published on this page, including changes to its content, evidence, conclusions, or author context. Internal processes and discussion activity are excluded. Pending, declined, and withdrawn proposals remain private.
No material page changes have been recorded yet.