While chromium (Cr)(III) deficiency may contribute to glucose intolerance, supplementation trials have produced inconsistent results. The disconnect between mechanistic plausibility and clinical trial evidence suggests that chromium supplementation may only benefit the subset of patients with genuine chromium deficiency rather than T2D patients broadly.

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This paradox is indexed from the dietary metal analysis in Type 2 Diabetes.

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Current recordThe chromium supplementation paradox — Type 2 DiabetesAnalyses
DiseasesType 2 DiabetesReferenced in this analyses recordAnalysesDietary Metal Paradoxes: When Healthy Foods and Good Intentions BackfireReferenced in this analyses record
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