Mechanisms5 sources
Indole and Indole Derivatives
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WikiBiomeThe human microbiome encyclopediaRanked matches across titles, topics, categories, and article introductions, filtered to mechanism.
This knowledge-base record is being expanded from WikiBiome’s evidence graph.
Microbial tryptophan metabolites produced by gut bacteria through the third branch of tryptophan metabolism -- the indole pathway. Unlike the host-dominated kynurenine pathway (~95% of Trp) and the serotonin pathway (~1-2%), the indole pathway is exclusively microbial a…
A three-carbon short-chain fatty acid (SCFA) produced primarily by Bacteroidetes and certain Firmicutes through anaerobic fermentation of dietary substrates. At physiological concentrations in healthy gut microbiomes, propionic acid (PPA) is a normal fermentation produc…