Mechanisms6 sources
Lipid Peroxidation
Lipid peroxidation is the oxidative degradation of polyunsaturated fatty acids (PUFAs) in cell membranes by reactive oxygen species (ROS). The process generates toxic aldehydes — malondialdehyde (MDA) and 4-hydroxynonenal (4-HNE) — that damage proteins, DNA, and mitocho…