Added “Corynebacterium”: Corynebacterium is a large genus of Gram-positive, club-shaped bacteria with over 130 species spanning commensals, opportunistic pathogens, and the classic pathogen C. diphtheriae. In the WikiBiome…
Added “Corynebacterium”: Corynebacterium is a large genus of Gram-positive, club-shaped bacteria with over 130 species spanning commensals, opportunistic pathogens, and the classic pathogen C. diphtheriae. In the WikiBiome… Added “Seminal Fluid Microbiome”: Corynebacterium is one of the core genera of the seminal fluid microbiome across multiple studies: - Identified as a dominant genus in seminal fluid alongside Staphylococcus, Streptococcus, and… Added “Prostate”: - Enriched in prostate cancer tissue compared to benign prostate. - Present in chronic bacterial prostatitis, where probiotic interventions alter Corynebacterium abundance. Added “Female Reproductive Tract”: - Identified in cervical mucus microbiome of endometriosis patients. - Part of the vaginal microbiota shifts observed in deep endometriosis. - Mucosal lactoferrin levels affect Corynebacterium… Added “Iron-Regulated Virulence”: The paradigm case is C. diphtheriae, whose diphtheria toxin gene (tox) is carried by a corynephage and is transcriptionally repressed by iron via the DtxR (diphtheria toxin repressor) regulator. Under… Added “Other Associations”: - ASD: Altered Corynebacterium abundance in gut microbiota of ASD children. - Cadmium exposure: Corynebacterium abundance altered by environmental cadmium in animal models. Added “Cross-References”: - iron — DtxR-mediated iron regulation controls virulence and siderophore production - lactoferrin — mucosal lactoferrin affects genital tract Corynebacterium colonization - nutritional immunity —… Added citations to “Seminal Fluid Microbiome”: molina morales 2023 male reproductive tract microbiome; javurek 2016 seminal fluid microbiome esr1; neto 2024 environmental factors seminal microbiome sperm quality; ughade 2024 genital dysbiosis fertility review; cai 2022 gut microbiota male reproduction. Added citations to “Prostate”: bautista 2025 reprogramming prostate cancer microbiome; vocca 2025 probiotics chronic bacterial prostatitis rct. Added citations to “Female Reproductive Tract”: akiyama 2019 cervical mucus microbial colonization endometriosis; ser 2023 current updates microbiome endometriosis review; hernandes 2020 microbiome profile deep endometriosis; macsharry 2024 endometriosis vaginal microbiota n glycome; roberts 2019 mucosal lactoferrin genital infections iron. Added citations to “Other Associations”: strati 2017 altered gut microbiota mycobiota asd; liu 2023 cadmium microbiota metabolome rats. Added references: molina-morales-2023-male-reproductive-tract-microbiome; javurek-2016-seminal-fluid-microbiome-esr1; neto-2024-environmental-factors-seminal-microbiome-sperm-quality; bautista-2025-reprogramming-prostate-cancer-microbiome; vocca-2025-probiotics-chronic-bacterial-prostatitis-rct; cai-2022-gut-microbiota-male-reproduction; ughade-2024-genital-dysbiosis-fertility-review; akiyama-2019-cervical-mucus-microbial-colonization-endometriosis; ser-2023-current-updates-microbiome-endometriosis-review; hernandes-2020-microbiome-profile-deep-endometriosis; macsharry-2024-endometriosis-vaginal-microbiota-n-glycome; roberts-2019-mucosal-lactoferrin-genital-infections-iron; strati-2017-altered-gut-microbiota-mycobiota-asd; liu-2023-cadmium-microbiota-metabolome-rats. Added key enzymes: siderophore-uptake-systems; diphtheria-toxin-iron-regulated. Added metal dependencies: iron.
wiki/entities/corynebacterium.md