Mechanisms8 sources
Hypoxic Signaling (HIF-1α Pathway)
Activation of the hypoxia-inducible factor pathway under normoxic conditions is a hallmark mechanism of nickel carcinogenesis, distinguishing it from arsenic and chromium.
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Activation of the hypoxia-inducible factor pathway under normoxic conditions is a hallmark mechanism of nickel carcinogenesis, distinguishing it from arsenic and chromium.
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