Revision history:
Mendelian Randomization

Created “Mendelian Randomization”: Mendelian randomization (MR) is a statistical method that uses genetic variants as instrumental variables to infer causal relationships between an exposure (e.g., gut microbiome composition) and an…

Created “Mendelian Randomization”: Mendelian randomization (MR) is a statistical method that uses genetic variants as instrumental variables to infer causal relationships between an exposure (e.g., gut microbiome composition) and an… Published sections: Overview; Core Design: Two-Sample MR; Statistical Methods; Limitations; Microbiome → Disease (Forward MR); Disease → Microbiome (Reverse MR); Metal → Disease (MR); Null Results (Equally Important); The Bifidobacterium Paradox; Bidirectional Vicious Cycles; Distinguishing Cause from Consequence; Relevance to WikiBiome; Cross-References.