Representative unstressed Bifidobacterium breve rod morphology, shown as seven cells in six groupings. This reconstruction is not diagnostic and is not a micrograph.
Scientific media record1 verified identifier
- Subject
- Bifidobacterium brevetaxon · species
- Identifiers
- NCBITaxon:1685
- Review
- Editorial review completeIdentifiers authority-verified · Accessibility validated · · bifidobacterium-breve|bifidobacterium-breve-morphology-v1.webp
- Digital source
- Trained-algorithmic mediaCreated with a trained generative algorithm and reviewed by WikiBiome for subject identity, scientific framing, identifiers, provenance, and accessibility.
- Scientific basis
- Bifidobacterium breve — NCBI TaxonomyBifidobacterium breve type strainBifid Shape Is Intrinsic to Bifidobacterium adolescentis
- License
- CC BY-SA 4.0Created
Bifidobacterium breve is a Gram-positive, obligate anaerobic species within the phylum Actinobacteria, predominantly found in the infant gut and breast milk. It is among the earliest colonizers of the neonatal intestine and plays a key role in human milk oligosaccharide metabolism.
As a widely studied probiotic species, B. breve has attracted attention for its immunomodulatory properties, particularly in neuropsychiatric contexts.
In a systematic review of probiotic interventions for schizophrenia, B. breve-containing formulations contributed to significant reductions in TNF-alpha levels, suggesting anti-inflammatory effects relevant to the gut-brain axis (,[1]A Systematic Review of the Effect of Probiotic Supplementation on Schizophrenia SymptomsNg QX, Soh AYS, Venkatanarayanan N et al. · 2019Open reference 1 ↓ systematic review).
The species has also been evaluated in autism spectrum disorder, where probiotic supplementation including B. breve showed potential for modulating gut-brain signaling and improving behavioral outcomes (,[2]Feng 2023 — Probiotics in Treatment of ASD: Gut-Brain Axis PerspectivesPengya Feng, Shuai Zhao, Yangyang Zhang et al. · 2023Open reference 2 ↓ review).
Evidence map1 cited passagesInspect provenance +
In a systematic review of probiotic interventions for schizophrenia, B. breve-containing formulations contributed to significant reductions in TNF-alpha levels, suggesting anti-inflammatory effects relevant to the gut-brain axis (, systematic review). The species has also been evaluated in autism spectrum disorder, where probiotic supplementation including B
Contents
1. Cross-ReferencesCross-References#
- Actinobacteria (Actinomycetota)—parent phylum
- Autism Spectrum Disorder—associated condition
- Schizophrenia—associated condition
- Gut-Brain Axis—primary mechanism of action
References 7
Numbered by first appearance in the article, then reconciled with its declared source list.
- 1
Ng QX, Soh AYS, Venkatanarayanan N et al. (2019). A Systematic Review of the Effect of Probiotic Supplementation on Schizophrenia Symptoms. Neuropsychobiology.
- 2
Pengya Feng, Shuai Zhao, Yangyang Zhang et al. (2023). Feng 2023 — Probiotics in Treatment of ASD: Gut-Brain Axis Perspectives. Frontiers in Microbiology.
- 3
Khatoon S, Kalam N, Rashid S et al. (2023). Effects of gut microbiota on neurodegenerative diseases. Frontiers in Aging Neuroscience.
- 4
Hooi-Leng Ser, Siu-Jung Au Yong, Mohamad Nasir Shafiee et al. (2023). Ser 2023 — Current Updates on the Role of Microbiome in Endometriosis: A Narrative Review. Microorganisms.
- 5
Ye N, Song X, Yu J et al. (2025). Effects of Gut Microbiota Interventions on Patients with Schizophrenia: A Systematic Review and Meta-Analysis. Frontiers in Microbiology.
- 6
Yasufumi Saito, Takao Hinoi, Tomohiro Adachi et al. (2019). Synbiotics suppress colitis-induced tumorigenesis in a colon-specific cancer mouse model. PLoS ONE.
- 7
Chen H, Wang L, Zhao L et al. (2021). Chen 2021 — Alterations of vaginal microbiota in women with infertility and Chlamydia trachomatis infection. Frontiers in Cellular and Infection Microbiology.
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