Ten slender tapered Rikenella rods appear in eight groups: six singles and two close pairs on a pale field.
Genus representative reconstruction Editorially reviewed

Type-species-anchored Rikenella reconstruction with ten tapered rods in six single and two paired groupings. The genus plate is representative, non-universal, non-diagnostic, and not a micrograph.

WikiBiome / Microbiome MedicineCurrent-genus-taxonomy-, original-reclassification-, type-species-, and output-audit-informed reconstruction
Scientific media record1 verified identifier
Subject
Rikenellataxon · genus
Review
Editorial review completeIdentifiers authority-verified · Accessibility validated · · rikenella|rikenella-morphology-v1.webp
Digital source
Trained-algorithmic mediaCreated with a trained generative algorithm and reviewed by WikiBiome for subject identity, scientific framing, identifiers, provenance, and accessibility.
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CC BY-SA 4.0Created

Rikenella is a genus of obligate anaerobic, Gram-negative bacteria in the family Rikenellaceae (phylum Bacteroidetes). The primary species is R. microfusus. In the WikiBiome vault, Rikenella is consistently depleted across disease states—a protective commensal whose loss is part of the dysbiotic signature.

Evidence map6 cited passagesInspect provenance +
01
Disease Associations

CVD: Bidirectional MR suggests causal protective association.

02
Disease Associations

Schizophrenia: Depleted in schizophrenia gut microbiome.

03
Disease Associations

T1D: Early-life antibiotic exposure depletes Rikenella, associated with autoimmune diabetes.

04
Disease Associations

Endometriosis: Depleted in endometriosis gut microbiota.

05
Disease Associations

Prostate: Part of altered gut microbiome in prostatic disease.

06
Disease Associations

QTL-linked: Abundance is genetically influenced (QTL-mapped) and responsive to diet and sex.

Contents1. Disease Associations2. Cross-References

Disease Associations#

CVD: Bidirectional MR suggests causal protective association.[1]Assessment of the Causal Relationship between Gut Microbiota and Cardiovascular Diseases: A Bidirectional Mendelian Randomization AnalysisXiao-Ce Dai, Yi Yu, Si-Yu Zhou et al. · 2024Open reference 1 Schizophrenia: Depleted in schizophrenia Gut Microbiome.[2]The Gut Microbiome and Schizophrenia: The Current State of the Field and Clinical ApplicationsSzeligowski T, Yun AL, Lennox BR et al. · 2020Open reference 2 T1D: Early-life antibiotic exposure depletes Rikenella, associated with autoimmune diabetes.[3]Candon 2015 — Antibiotics in Early Life Alter the Gut Microbiome and Increase Disease Incidence in a Spontaneous Mouse Model of Autoimmune DiabetesSophie Candon, Alicia Perez-Arroyo, Cindy Marquet et al. · 2015Open reference 3

Endometriosis: Depleted in endometriosis gut microbiota.[4]Associations Between Endometriosis and Gut MicrobiotaSvensson A, Brunkwall L, Roth B et al. · 2021Open reference 4 Prostate: Part of altered gut microbiome in prostatic disease.[5]Cao 2024 — Gut Microbiome: A Novel Preventive and Therapeutic Target for Prostatic DiseaseHongliang Cao, Difei Zhang, Pengyu Wang et al. · 2024Open reference 5 QTL-linked: Abundance is genetically influenced (QTL-mapped) and responsive to diet and sex.[6]Salvador 2023 — Strain, Sex, and Diet-Dependent Modulation of Gut Microbiota Reveals Candidate Keystone OrganismsAnna C. Salvador, M. Nazmul Huda, Danny Arends et al. · 2023Open reference 6

Cross-References#

Generated evidence record

References 6

Numbered by first appearance in the article, then reconciled with its declared source list.

  1. 1

    Xiao-Ce Dai, Yi Yu, Si-Yu Zhou et al. (2024). Assessment of the Causal Relationship between Gut Microbiota and Cardiovascular Diseases: A Bidirectional Mendelian Randomization Analysis. BioData Mining.

  2. 2

    Szeligowski T, Yun AL, Lennox BR et al. (2020). The Gut Microbiome and Schizophrenia: The Current State of the Field and Clinical Applications. Frontiers in Psychiatry.

  3. 3

    Sophie Candon, Alicia Perez-Arroyo, Cindy Marquet et al. (2015). Candon 2015 — Antibiotics in Early Life Alter the Gut Microbiome and Increase Disease Incidence in a Spontaneous Mouse Model of Autoimmune Diabetes. PLoS ONE.

  4. 4

    Svensson A, Brunkwall L, Roth B et al. (2021). Associations Between Endometriosis and Gut Microbiota. Reproductive Sciences.

  5. 5

    Hongliang Cao, Difei Zhang, Pengyu Wang et al. (2024). Cao 2024 — Gut Microbiome: A Novel Preventive and Therapeutic Target for Prostatic Disease. Frontiers in Cellular and Infection Microbiology.

  6. 6

    Anna C. Salvador, M. Nazmul Huda, Danny Arends et al. (2023). Salvador 2023 — Strain, Sex, and Diet-Dependent Modulation of Gut Microbiota Reveals Candidate Keystone Organisms. Microbiome.

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2 events
  1. published revision

    Backfill gut microbiome concept links

    Karen Pendergrass · +1 −1

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  2. published revision

    massive wiki expansion: 149 stubs fixed, 100+ new pages, Rule 15 scan, keystone papers

    WikiBiome Deploy Bot · +45 −0

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6 references · 0 backlinks · 9 indexed topics