Type-species-anchored Olsenella elliptical rods, shown as eleven bodies in six single, one paired, and one three-body chain grouping. This genus-level scientific reconstruction is representative, non-universal, non-diagnostic, and not a micrograph.
Scientific media record1 verified identifier
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- Olsenellataxon · genus
- Identifiers
- NCBITaxon:133925
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- Editorial review completeIdentifiers authority-verified · Accessibility validated · · olsenella|olsenella-morphology-v1.webp
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Olsenella is a Gram-positive obligate anaerobic genus within the Coriobacteriaceae (Actinobacteria). Species such as O. uli and O. profusa were originally isolated from the oral cavity but are increasingly detected in Gut Microbiome surveys, particularly in disease states.
Metal Dependencies#
Olsenella species require iron and manganese for their fermentative metabolism. Their lactic acid output can lower local pH, which in turn increases the solubility and bioavailability of metal ions—creating a feedback loop that may alter the competitive landscape for metal-dependent organisms in the immediate vicinity.
Ecological Role#
Olsenella is a lactic acid fermenter that thrives in carbohydrate-rich, anaerobic environments. In the oral cavity, it contributes to dental caries through acid production. Its presence in the gut likely reflects oral-to-gut translocation during barrier compromise, a pattern discussed for other oral taxa such as Lancefieldella parvula and Fusobacterium nucleatum.
Conditions Associated#
Gut enrichment of Olsenella has been reported in Inflammatory Bowel Disease (IBD) and Colorectal Cancer cohorts. In the oral niche, it associates with deep carious lesions. Its dual-compartment presence makes it a candidate marker for assessing oral-gut barrier integrity.
Cross-References#
- Iron—metabolic requirement
- Fusobacterium nucleatum—shared oral-to-gut translocation
- Colorectal Cancer—gut enrichment in disease
- pH Sensing—acid production altering metal bioavailability
References 6
Numbered by first appearance in the article, then reconciled with its declared source list.
- 1
Wang et al. (2024). Wang 2024 — Gut Microbiota and Fibromyalgia (Mendelian Randomization). Frontiers in Microbiology.
- 2
Hou X, Zheng Z, Wei J et al. (2022). Effects of Gut Microbiota on Immune Responses and Immunotherapy in Colorectal Cancer. Frontiers in Immunology.
- 3
Ning Sun, Yong Chen, Jiaxun Zhang et al. (2023). Identification and characterization of pancreatic infections in severe and critical acute pancreatitis patients using 16S rRNA gene next generation sequencing. Frontiers in Microbiology.
- 4
Simeng Liu, Enyao Li, Zhenyu Sun et al. (2019). Liu 2019 — Altered Gut Microbiota and Short Chain Fatty Acids in Chinese Children with Autism Spectrum Disorder. Scientific Reports.
- 5
C. Iannuccelli, M. Favretti, G. Dolcini et al. (2025). Iannuccelli 2025 — Fibromyalgia: One Year in Review 2025. Clinical and Experimental Rheumatology.
- 6
Ye Liang, Weihong Zeng, Tao Hou et al. (2023). Liang 2023 — Gut Microbiome and Reproductive Endocrine Diseases (MR Study). Frontiers in Endocrinology.
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