Bifidobacterium bifidum is an obligate anaerobic, Gram-positive species that specializes in human milk oligosaccharide (HMO) and mucin glycan degradation. It is one of the earliest colonizers of the infant gut and a widely used probiotic species.
Key Associations
- Lead sensitivity: Prenatal lead exposure depletes B. bifidum in childhood gut microbiome, suggesting metal vulnerability eggers 2023 prenatal lead childhood gut microbiome progress.
- Schizophrenia RCT: Component of probiotic formulation (with L. acidophilus) + vitamin D improving metabolic parameters in schizophrenia ghaderi 2019 vitamin d probiotic schizophrenia metabolic rct.
- Male fertility: Oxidative stress modulation via gut microbiota kurhaluk 2025 oxidative stress gut microbiota male fertility.
- CRC-adenoma: Altered in CRC progression li 2023 combined gut bacteria fungi crc adenoma chinese cohort.
Cross-References
- bifidobacterium — genus page
- lead — prenatal exposure depletes B. bifidum
- bifidobacteriaceae — family context