Bifidobacterium bifidum

Key Associations#

Lead sensitivity: Prenatal lead exposure depletes B. bifidum in childhood Gut Microbiome, suggesting metal vulnerability.^{[1]Eggers 2023 — Prenatal lead exposure is negatively associated with gut microbiome in childhood (PROGRESS cohort)Shoshannah Eggers, Vishal Midya, Moira Bixby et al. · 2023Open reference 1 ↓}

Schizophrenia RCT: Component of probiotic formulation (with L. acidophilus) + vitamin D improving metabolic parameters in schizophrenia.^{[2]Clinical and Metabolic Response to Vitamin D Plus Probiotic in Schizophrenia PatientsGhaderi A, Banafshe HR, Mirhosseini N et al. · 2019Open reference 2 ↓}

Male fertility: Oxidative Stress modulation via gut microbiota.^{[3]Kurhaluk 2025 — Oxidative Stress, Antioxidants, Gut Microbiota and Male FertilityNatalia Kurhaluk, Piotr Kaminski, Halina Tkaczenko · 2025Open reference 3 ↓} CRC-adenoma: Altered in CRC progression.^{[4]Features of combined gut bacteria and fungi from a Chinese cohort of colorectal cancer, colorectal adenoma, and post-operative patientsXiaopeng Li, Jiahui Feng, Zhanggui Wang et al. · 2023Open reference 4 ↓}