Overview
Harm potential: GREEN — PPIs remain appropriate first-line therapy; this STOP recommends co-administration of probiotics, not PPI avoidance.
STOP: Long Term PPI Monotherapy Without Microbiome Support In GERD
References (4)
- . yin 2025 probiotics ppi gerd rct
- . shi 2023 ppi fungal dysbiosis gerd
- . park 2020 nerd treatment esophageal microbiome
- . deshpande 2018 esophageal microbiome signatures host genetics