Eleven selected Mycoplasma rounded-to-ovoid bodies appear in eight groupings: five singles and three touching pairs.
Current-genus representative reconstruction Editorially reviewed

Current-genus, type-species-anchored Mycoplasma wall-less forms, shown as eleven bodies in five single and three paired groupings. This scientific reconstruction is representative, non-universal, non-diagnostic, and not a micrograph.

WikiBiome / Microbiome MedicineCurrent-conserved-genus-taxonomy-, nomenclature-, type-species-, and primary-structure-informed representative reconstruction
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Mycoplasmataxon · genus
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Editorial review completeIdentifiers authority-verified · Accessibility validated · · mycoplasma|mycoplasma-morphology-v1.webp
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Mycoplasma is a genus of wall-less bacteria in the class Mollicutes, characterized by the smallest genomes of any self-replicating organisms (~580–1,350 kb). The lack of a cell wall makes them intrinsically resistant to beta-lactam antibiotics and undetectable by Gram staining.

Key human-pathogenic species include M. pneumoniae (atypical pneumonia), M. genitalium (STI), and M. hominis (urogenital infections).

Like Ureaplasma (a fellow Mollicute), Mycoplasma species are parasitic, depending on host cells for nutrients they cannot synthesize—including cholesterol for membrane stability.

Evidence map6 cited passagesInspect provenance +
01
Reproductive Tract Associations

Prostatitis: M. hominis and M. genitalium detected in prostatic secretions of chronic prostatitis patients.

02
Reproductive Tract Associations

Male infertility: Mycoplasma colonization of seminal fluid associated with reduced sperm quality.

03
Reproductive Tract Associations

Endometriosis: Part of vaginal microbiome shifts in endometriosis patients.

04
Gut and Systemic Associations

Multiple sclerosis: Mycoplasma detected in gut microbiome studies of MS patients.

05
Gut and Systemic Associations

Crohn's disease: Part of gut microbiome shifts during Crohn's remission/relapse cycles.

06
Gut and Systemic Associations

Oral microbiome: Affected by common medications.

Contents1. Reproductive Tract Associations2. Gut and Systemic Associations3. Cross-References

Reproductive Tract Associations#

Prostatitis: M. hominis and M. genitalium detected in prostatic secretions of chronic prostatitis patients.[1]Magri 2018 — Multidisciplinary Approach to ProstatitisVittorio Magri, Matteo Boltri, Tommaso Cai et al. · 2018Open reference 1 Male infertility: Mycoplasma colonization of seminal fluid associated with reduced sperm quality.[2]Magill 2023 — Male Infertility and the Human MicrobiomeMagill RG, MacDonald SM · 2023Open reference 2

Endometriosis: Part of vaginal microbiome shifts in endometriosis patients.[3]Shen 2022 — Vaginal Microecological Characteristics of Women in Different Physiological and Pathological PeriodsLiping Shen, Wei Zhang, Yi Yuan et al. · 2022Open reference 3

Gut and Systemic Associations#

Multiple sclerosis: Mycoplasma detected in Gut Microbiome studies of MS patients.[4]Feeding the gut microbiome: impact on multiple sclerosisMatteo Bronzini, Alessandro Maglione, Rachele Rosso et al. · 2023Open reference 4 Crohn's disease: Part of gut microbiome shifts during Crohn's remission/relapse cycles.[5]Crohn's Disease in Endoscopic Remission, Obesity, and Cases of High Genetic Risk Demonstrate Overlapping Shifts in the Colonic Mucosal-Luminal Interface MicrobiomeJacobs JP, Goudarzi M, Lagishetty V et al. · 2022Open reference 5 Oral microbiome: Affected by common medications.[6]Investigation of the impact of commonly used medications on the oral microbiome of individuals living without major chronic conditionsVanessa DeClercq, Jacob T. Nearing, Morgan G.I. Langille · 2021Open reference 6

Cross-References#

  • Ureaplasma—sister Mollicute genus; shares wall-less biology and urogenital niche
  • Endometriosis—vaginal microbiome associations
  • Propionic Acid—some Mycoplasma species produce propionate
Generated evidence record

References 6

Numbered by first appearance in the article, then reconciled with its declared source list.

  1. 1

    Vittorio Magri, Matteo Boltri, Tommaso Cai et al. (2018). Magri 2018 — Multidisciplinary Approach to Prostatitis. Archivio Italiano di Urologia e Andrologia.

  2. 2

    Magill RG, MacDonald SM (2023). Magill 2023 — Male Infertility and the Human Microbiome. Frontiers in Reproductive Health.

  3. 3

    Liping Shen, Wei Zhang, Yi Yuan et al. (2022). Shen 2022 — Vaginal Microecological Characteristics of Women in Different Physiological and Pathological Periods. Frontiers in Cellular and Infection Microbiology.

  4. 4

    Matteo Bronzini, Alessandro Maglione, Rachele Rosso et al. (2023). Feeding the gut microbiome: impact on multiple sclerosis. Frontiers in Immunology.

  5. 5

    Jacobs JP, Goudarzi M, Lagishetty V et al. (2022). Crohn's Disease in Endoscopic Remission, Obesity, and Cases of High Genetic Risk Demonstrate Overlapping Shifts in the Colonic Mucosal-Luminal Interface Microbiome. Genome Medicine.

  6. 6

    Vanessa DeClercq, Jacob T. Nearing, Morgan G.I. Langille (2021). Investigation of the impact of commonly used medications on the oral microbiome of individuals living without major chronic conditions. PLoS ONE.

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